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PROF LOUISE BURRELL



Contact Details

Organization: Medicine - Austin Health and Northern Health
Position: PROFESSOR
Email:
Work: 9494 2159
Fax: 9497 4554
Level: 01
Building: No Building
Campus: Repatriation Hospital

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Medicine and Bachelor of Surgery University of Dundee 01-Aug-1984
Doctor of Medicine University of Dundee 31-Dec-1992

Memberships

Membership Type Membership Body Description Start Date End Date
Council International Society of Hypertension Executive member, Treasurer 01-Sep-2009
Council High Blood Pressure Research Council of Australia Member 01-Jan-2005 31-Dec-2010

Fellowships

Fellowship Date Awarded
Fellow of the Royal Australasian College of Physicians (FRACP)
Member of the Royal College of Physicians of London (MRCP) 01-Nov-1987

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Cardiac disease in experimental diabetes; intervention studies Chief Investigator NATIONAL HEART FOUNDATION Grants-in-Aid 01/01/2004
THE ROLE OF VASOACTIVE HORMONES IN PROGRESSIVE LIVER DISEASE Chief Investigator NHMRC Project Grants 01/01/2005
SYNERGY HT MULTI-DETECTION MICROPLATE READER Chief Investigator PERPETUAL TRUSTEES AUST LTD Clive & Vera Ramaciotti Establishment Grant 01/01/2007
CHARACTERIZATION OF THE RENIN-ANGIOTENSIN SYSTEM IN THE DISEASED BLOOD VESSELS WITH IMPAIRED/ABROGATED ENDOTHELIAL FUNCTION Chief Investigator NATIONAL HEART FOUNDATION Grants-in-Aid 01/01/2007
Do Abnormalities on cardiac echocardiography predict adverse cardiovascular outcomes in patients with diabetes? Chief Investigator AUSTRALIAN DIABETES SOCIETY ADS Servier Diabetes Grants in Memory of Barry Young 10/10/2007
Novel markers of myocardial injury in man Principal Supervisor ROYAL AUST COLLEGE OF PHYSICIANS Research Fellowship (ROYAL AUSTRALASIAN COLLEGE OF PHYSICIANS) 20/10/2007
Novel vasoactive components in liver disease Chief Investigator NHMRC Project Grants 01/01/2008
NOVEL APPROACHES TO RISK STRATIFICATION IN PATIENTS WITH TYPE 2 DIABETES Chief Investigator NHMRC Project Grants 01/01/2008
NOVEL COMPONENTS OF THE RENIN-ANGIOTENSIN SYSTEM IN CARDIAC DISEASE Principal Supervisor NATIONAL HEART FOUNDATION Postgraduate Medical Research Scholarships 01/01/2008
The Vivid i Ultra-Portable Echo System Chief Investigator PERPETUAL TRUSTEES AUST LTD Clive & Vera Ramaciotti Equipment Grants 10/10/2008
Vasopressin and heart failure Chief Investigator NHMRC Project Grants 01/01/2009
Diabetic heart disease Chief Investigator NATIONAL HEART FOUNDATION Grants-in-Aid 01/01/2009
Aortic Stenosis: Mechanisms and Prognostic Markers in Man Principal Supervisor NATIONAL HEART FOUNDATION Postgraduate Research Scholarship 01/01/2009
Echocardiographic predictors of cardiovascular outcomes and their progression in diabetes mellitus Principal Supervisor NATIONAL HEART FOUNDATION Postgraduate Research Scholarship 01/01/2009
Novel markers of cardiac injury in patients with stable and unstable coronary syndromes Principal Supervisor NATIONAL HEART FOUNDATION Postgraduate Research Scholarship 01/01/2009
Heart Disease and Type 2 Diabetes Mellitus Principal Supervisor NHMRC Scholarships 01/01/2009

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Portal pressure responses and angiotensin peptide production in rat liver are determined by relative activity of ACE and ACE2


    Year: 2009
    Journal: American Journal of Physiology: Gastrointestinal and Liver Physiology
    Volume: 297
    Issue: 1
    Page numbers: G98-G106
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  • Angiotensin 1-7, an alternative metabolite of the reninangiotensin system, is upregulated in human liver disease and has antifibrotic activity in the bile duct ligated rat
    Year: 2009
    Journal: Clinical Science
    Volume: 117
    Issue: 11
    Page numbers: 375-386
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Publications in 2008

Journal Articles

  • ACE2 and AT4R are present in diseased human blood vessels
    Year: 2008
    Journal: European Journal of Histochemistry
    Volume: 52
    Issue: 1
    Page numbers: 39-44
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  • Acute kidney injury in the rat causes cardiac remodelling and increases angiotensin-converting enzyme 2 expression
    Year: 2008
    Journal: Experimental Physiology
    Volume: 93
    Issue: 5
    Page numbers: 622-630
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  • Angiotensin converting enzyme 2 (ACE2) activity in fetal calf serum: implications for cell culture research
    Year: 2008
    Journal: Cytotechnology
    Volume: 58
    Page numbers: 119-126
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  • Angiotensin-converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor
    Year: 2008
    Journal: Experimental Physiology
    Volume: 93
    Issue: 5
    Page numbers: 685-693
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  • Association between intrarenal arterial resistance and diastolic dysfunction in type 2 diabetes

    Year: 2008
    Journal: Cardiovascular Diabetology
    Volume: 7
    Issue: 2008
    Page numbers: 7-15
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  • Co-localization of angiotensin-converting enzyme 2-, octomer-4- and CD34-positive cells in rabbit atherosclerotic plaques
    Year: 2008
    Journal: Experimental Physiology
    Volume: 93
    Issue: 5
    Page numbers: 564-569
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  • Early undernutrition leads to long-lasting reductions in body weight and adiposity whereas increased intake increases cardiac fibrosis in male rats.
    Year: 2008
    Journal: Journal of Nutrition
    Volume: 138
    Page numbers: 1622-1627
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  • Liver disease and the renin-angiotensin system: Recent discoveries and clinical implications
    Year: 2008
    Journal: Journal of Gastroenterology and Hepatology
    Volume: 23
    Issue: Sep
    Page numbers: 1327-38
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  • Prevalence and predictors of cardiac hypertrophy and dysfunction in patients with Type 2 diabetes
    Year: 2008
    Journal: Clinical Science
    Volume: 114
    Issue: 2008
    Page numbers: 313-320
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Publications in 2007

Journal Articles

  • ACE2 and Diabetic Complications
    Year: 2007
    Journal: Current Pharmaceutical Design
    Volume: 13
    Issue: 26
    Page numbers: 2730-2735
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  • Prevalence and predictors of cardiac hypertrophy and dysfunction in patients with type 2 diabetes
    Year: 2007
    Journal: Clinical Science
    Volume: 2007
    Issue: 2007
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  • Upregulation of hepatic angiotensin-converting enzyme 2 (ACE2) and angiotensin-(1-7) levels in experimental biliary fibrosis
    Year: 2007
    Journal: Hepatology
    Volume: 47
    Issue: 3
    Page numbers: 387-395
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Publications in 2006

Journal Articles

  • Diastolic dysfunction is associated with anaemia in patients with Type 11 diabetes
    Year: 2006
    Journal: Clinical Science
    Volume: 110
    Issue: 2006
    Page numbers: 109-116
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  • Guidelines for the prevention, detection and management of people with chronic heart failure in Australia 2006
    Year: 2006
    Journal: Medical Journal of Australia
    Volume: 185
    Issue: 2006
    Page numbers: 549--556
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  • Immunolocalization of ACE2 and AT2 receptors in rabbit atherosclerotic plaques
    Year: 2006
    Journal: Journal of Histochemistry and Cytochemistry
    Volume: 54(2)
    Issue: 2006
    Page numbers: 147-150
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  • Optimizing heart failure management: An Australian experience
    Year: 2006
    Journal: International Journal of Cardiology
    Volume: 112
    Issue: 2006
    Page numbers: 256
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  • Vascular neutral endopeptidase inhibition imiproves endothelial function and reduces intimal hyperplasia
    Year: 2006
    Journal: Cardiovascular Research
    Volume: 71
    Issue: 2006
    Page numbers: 179-188
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Publications in 2005

Journal Articles

  • An unexpected cause of macroscopic haematuria
    Year: 2005
    Journal: Medical Journal of Australia
    Volume: 183
    Issue: 321-323
    Page numbers: 6
    Publisher: Australasian Medical Publishing Co Ltd(Sydney)
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  • Anti-atherosclerotic and renoprotective effects of combined angiotensin-converting enzyme and neutral endopeptidase inhibition in diabetic apolipoprotein E-knockout mice
    Year: 2005
    Journal: Journal of Hypertension
    Volume: 23
    Page numbers: 2071-2082
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2
    Year: 2005
    Journal: Gut
    Volume: 54
    Page numbers: 1790-1796
    Publisher: British Medical Journal Publishing Group(London)
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  • Connective tissue growth factor and cardiac fibrosis after Myocardial infarction
    Year: 2005
    Journal: Journal of Histochemistry and Cytochemistry
    Volume: 53
    Page numbers: 1245-1256
    Publisher: Histochemical Society(Seattle)
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  • Glomerular Permeability Defect in Hypertension is dependent on Renin Angiotensin System activation
    Year: 2005
    Journal: American Journal of Hypertension
    Volume: 18
    Page numbers: 844-850
    Publisher: Elsevier Science(New York)
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  • Immunolocalization of ACE2 and AT2 receptors in rabbit atherosclerotic plaques
    Year: 2005
    Journal: Journal of Histochemistry and Cytochemistry
    Volume: 54
    Page numbers: 147-150
    Publisher: Histochemical Society(Seattle)
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  • Lateral vs medial mitral annular tissue Doppler in the echocardiographic assessment of diastolic function and filling pressures: which should we use?
    Year: 2005
    Journal: European Journal of Echocardiography
    Volume: 6
    Page numbers: 97-106
    Publisher: WB Saunders Co(London)
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  • Myocardial infarction increases ACE2 expression in rat and humans
    Year: 2005
    Journal: European Heart Journal
    Volume: 26
    Page numbers: 369-375
    Publisher: WB Saunders Co
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Publications in 2004

Journal Articles

  • ACE2, a new regulator of the renin-angiotensin system
    Year: 2004
    Journal: Trends in Endocrinology and Metabolism
    Volume: 15
    Issue: 4 - May
    Page numbers: 166-169
    Publisher: Elsevier Science London(London)
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  • Cardiorenal protective effects of vasopeptidase inhibition with omapatrilat in hypertensive transgenic (mREN-2)27 rats
    Year: 2004
    Journal: Clinical and Experimental Hypertension
    Volume: 26
    Issue: 1
    Page numbers: 69-80
    Publisher: Marcel Dekker(New York)
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  • Diabetic Pyomyositis
    Year: 2004
    Journal: Diabetes Care
    Volume: 27
    Issue: 7
    Page numbers: 1743-1744
    Publisher: American Diabetes Association(Virginia)
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  • Thiazolidinediones and congestive heart failure-exacerbation or new onset of left ventricular dysfunction?
    Year: 2004
    Journal: Diabetic Medicine
    Volume: 21
    Page numbers: 945-950
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Publications in 2003

Journal Articles

  • A breaker of advanced Glycation end products attenuates diabetes-induced myocardial structural changes
    Year: 2003
    Journal: Circulation Research
    Volume: 92
    Page numbers: 785-792
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Cardiovascular hypertrophy in diabetic spontaneously hypertensive rats: optimizing blockade of the renin-angiotensin system
    Year: 2003
    Journal: Clinical Science
    Volume: 104
    Page numbers: 341-347
    Publisher: Portland Press(London)
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  • Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy
    Year: 2003
    Journal: Hypertension
    Volume: 41
    Page numbers: 392-397
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Diabetes mellitus: a cardiovascular disease
    Year: 2003
    Journal: Current Opinion in Investigational Drugs
    Volume: 4
    Issue: 9
    Page numbers: 1088-1094
    Publisher: Current Drugs
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  • Differential tissue and enzyme inhibitory effects of the vasopeptidase inhibitor omapatrilat in the rat
    Year: 2003
    Journal: Clinical Science
    Volume: 105
    Page numbers: 339-345
    Publisher: Portland Press(London)
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  • Renoprotective effects of vasopeptidase inhibition in an experimental model of diabetic nephropathy
    Year: 2003
    Journal: Diabetologia
    Volume: 46
    Page numbers: 961-971
    Publisher: Springer Verlag(New York)
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  • Upregulation of cardiac insulin-like growth factor-I receptor by ACE inhibition after myocardial infarction: potential role in remodeling
    Year: 2003
    Journal: Journal of Histochemistry and Cytochemistry
    Volume: 51
    Issue: 6
    Page numbers: 831-839
    Publisher: Histochemical Society(Seattle)
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  • Vasopressin Receptor Expression in the Placenta
    Year: 2003
    Journal: Biology of Reproduction
    Volume: 69
    Page numbers: 679-686
    Publisher: Society for the Study of Reproduction(Wisconsin)
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Publications in 2002

Journal Articles

  • Combined inhibition of neutral endopeptidase with angiotensin converting enzyme or endothelin converting enzyme in experimental diabetes
    Year: 2002
    Journal: Journal of Hypertension
    Volume: 20
    Page numbers: 707-714
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Inhibition of peptidases in the control of blood pressure
    Year: 2002
    Journal: Essays in Biochemistry
    Volume: 38
    Page numbers: 129-139
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  • Neurohormonal antagonism in heart failure; beneficial effects of vasopressin V1a and V2 receptor blockade and ACE inhibition
    Year: 2002
    Journal: Cardiovascular Research
    Volume: 54
    Page numbers: 51-57
    Publisher: Elsevier Science(Amsterdam)
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  • Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy
    Year: 2002
    Journal: Diabetes
    Volume: 51
    Page numbers: 3274-3282
    Publisher: American Diabetes Association(Virginia)
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  • Up-regulation of components of the renin-angiotensin system in the bile duct-ligated liver
    Year: 2002
    Journal: Gastroenterology
    Volume: 123
    Page numbers: 1667-1676
    Publisher: WB Saunders Co(Pennsylvania)
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Publications in 2001

Journal Articles

  • Endocrinology and metabolism meet in the heart
    Year: 2001
    Journal: Trends in Endocrinology and Metabolism
    Volume: 12
    Issue: 4
    Page numbers: 144-145
    Publisher: Elsevier Science London(London)
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  • Evidence for cardioprotective, renoprotective, and vasculoprotective effects of vasopeptidase inhibitors in disease
    Year: 2001
    Journal: Current Hypertension Reports
    Publisher: Current Science(London)
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  • In-vitro and in-vivo inhibition of rat neutral endopeptidase and angiotensin converting enzyme with the vasopeptidase inhibitor gemopatrilat
    Year: 2001
    Journal: Journal of Hypertension
    Volume: 19
    Page numbers: 941-946
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Vasopeptidase inhibition attenuates the progression of renal injury in subtotal nephrectomized rats
    Year: 2001
    Journal: Kidney International
    Volume: 60
    Page numbers: 715-721
    Publisher: Blackwell Science(Massachusetts)
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