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DR HEATHER STANTON



Contact Details

Organization: Paediatrics Royal Children's Hospital
Position: RESEARCH OFFICER
Email:

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Paedaitrics Paedaitrics Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science (Honours) University of Tasmania 17-Dec-1987
Doctor of Philosophy The Open University 11-Mar-1999

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Cartilage destruction in arthritis: mechanism of aggrecanase and matrix metalloproteinase action in vivo and in vitro Chief Investigator NHMRC Project Grants 01/01/2001
Cartilage destruction in arthritis: mechanism of aggrecanase and matrix metalloproteinase action in vivo and in vitro Chief Investigator NHMRC Research Fellowship 01/01/2001
Cartilage destruction in joint disease: studies with ADAMTS-4 and ADAMTS-5 deficient mice Chief Investigator NHMRC Project Grants 01/01/2005

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • Evidence for a novel aggrecan degrading activity in articular cartilage: studies of mice deficient in both ADAMTS-4 and ADAMTS-5


    Year: 2008
    Journal: Arthritis and Rheumatism
    Volume: 58
    Issue: 6
    Page numbers: 1664-1673
    Author(s):
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  • ADAMTS-5: the story so far
    Year: 2008
    Journal: European Cells & Materials
    Volume: 15
    Page numbers: 11-26
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Publications in 2007

Journal Articles

  • ADAMTS-5 deficiency does not block aggrecanolysis at preferred cleavage sites in the chondroitin sulphate-rich region of aggrecan.
    Year: 2007
    Journal: Journal of Biological Chemistry
    Volume: 282
    Issue: 12
    Page numbers: 8632-8640
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Conference Publications/Papers

  • ADAMTS-5 activity in synovial fibroblasts is different to chondrocytes
    Year: 2007
    Event name: Orthopaedic Research Society Conference 2007
    Conference Publication: Trans. Orthp.Res. Soc.
    Volume: 32
    Page numbers: 576
    Publisher: Orthopaedic Research Society(Dallas)
    Author(s):
  • Aggrecan catabolism in mice lacking both ADAMTS-4 and ADAMTS-5 activities: evidence for another aggrecanase in cartilage
    Year: 2007
    Event name: Orthopaedic Research Society Conference 2007
    Conference Publication: Trans Orth Res Soc 2007
    Volume: 32
    Page numbers: 82
    Publisher: Orthopaedic Research Society(Dallas)
    Author(s):

Publications in 2005

Journal Articles

  • ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
    Year: 2005
    Journal: Nature
    Volume: 434
    Issue: 7033
    Page numbers: 648-652
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Conference Publications/Papers

  • ADAMTS-5 is the major aggrecanase in cartilage: In vitro studies with ADAMTS-4 and ADAMTS-5 deficient mice
    Year: 2005
    Event name: Orthopaedic Research Society Conference 2006
    Conference Publication: Trans Orth Res Soc 2005
    Volume: 30
    Page numbers: 206
    Publisher: Orthopaedic Research Society(Dallas)
    Author(s):

Publications in 2004

Journal Articles

  • Cortisol enhances structural maturation of the hypoplastic fetal lung in sheep.
    Year: 2004
    Journal: The Journal of Physiology
    Volume: 554
    Issue: 2
    Page numbers: 505-517
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Publications in 2003

Journal Articles

  • Neoepitopes as biomarkers of cartilage catabolism.
    Year: 2003
    Journal: Inflammation Research
    Volume: 52
    Issue: 7
    Page numbers: 277-282
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Publications in 2002

Journal Articles

  • Matrix metalloproteinases are active following guanidine hydrochloride extraction of cartilage: generation of DIPEN neopitope dialysis
    Year: 2002
    Journal: Matrix Biology
    Volume: 21
    Page numbers: 425-428
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  • The 45 kDa collagen-binding fragment of fibronectin induces matrix metalloproteinasw-13 synthesis by chondrocytes and aggrecan degradation by aggrecanases
    Year: 2002
    Journal: Biochemical Journal
    Volume: 364
    Page numbers: 181-190
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Conference Publications/Papers

  • The collagen-binding fragment of fibtonectin induces MMP-13 synthesis by chondrocytes and aggrecan degradation by aggrecanases
    Year: 2002
    Event name: Orthopaedic Research Society 48th Annual Meeting
    Conference Publication: Trans Orthop Res Soc
    Volume: 27
    Page numbers: 156
    Publisher: Orthoptic Association of Australia
    Author(s):
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