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PROF RICHARD COTTON



Contact Details

Organization: Medicine - St Vincent's Hospital
Position: Honorary (Professorial Fellow)
Email:
Homepage: www.genomic.unimelb.edu.au
Work: 03 8344 1893
Fax: 03 9347 6842
Level: 02
Building: Alan Gilbert Building
Campus: Parkville

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Agricultural Science Institution not known 31-Dec-1963
Doctor of Science Institution not known 31-Dec-1983
Doctor of Philosophy Institution not known 31-Dec-1967

Honours

Honour Date Awarded
Member of the Order of Australia 2005

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Oxidation of mismatch: a new concept for mutation detection which avoids a separation method in mutation scanning Chief Investigator NHMRC Development Grants 01/01/2004
DEVELOPMENT OF A SIMPLE CHEMICAL TEST FOR DETECTING DNA-INTERACTING COMPOUNDS FOR MEDICAL AND ENVIRONMENTAL PURPOSES Chief Investigator NHMRC Development Grants 01/01/2005
Research Fellowship Chief Investigator NHMRC Research Fellowship 01/01/2005
DEVELOPMENT OF A SIMPLE, NOVEL CHEMICAL ASSAY FOR DETECTING DNA-INTERACTING COMPOUNDS Chief Investigator ANZ CHARITABLE TRUSTS Medical Research and Technology Grants 22/11/2006

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • The human variome project


    Year: 2008
    Journal: Science
    Volume: 322
    Page numbers: 861-862
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  • A  New Cover and New Challenges for Human Mutation
    Year: 2008
    Journal: Human Mutation
    Volume: 29
    Issue: 1
    Page numbers: 1
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  • General mutation databases: analysis and review
    Year: 2008
    Journal: Journal of Medical Genetics
    Volume: 45
    Issue: 2
    Page numbers: 65-70
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  • Human Variome Project: progress and plans
    Year: 2008
    Journal: Personalized Medicine
    Volume: 5
    Issue: 2
    Page numbers: 99-100
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  • Recommendations for Locus-Specific Databases and Their Curation
    Year: 2008
    Journal: Human Mutation
    Volume: 29
    Issue: 1
    Page numbers: 2-5
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  • VariVis: a visualisation toolkit for variation databases
    Year: 2008
    Journal: BMC Bioinformatics
    Volume: 9
    Issue: 206
    Page numbers: 1-5
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Publications in 2007

Journal Articles

  • A survey of locus-specific database curation
    Year: 2007
    Journal: Journal of Medical Genetics
    Volume: 44
    Issue: 4
    Page numbers: e72
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Publications in 2006

Book Chapters

  • The use of chemical cleavage of mismatch (CCM) for mutation detection
    Year: 2006
    Book: Genetic Variance Detection: Technologies for Pharmacogenomics
    Publisher: DNA Press
    Authors(s):
    Editors(s):

Journal Articles

  • Chemical cleavage of mismatch (CCM) to locate base mismatches in heteroduplex DNA
    Year: 2006
    Journal: Nature Protocols
    Volume: 1
    Issue: 5
    Page numbers: 2297-304
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  • Detection of 100% of mutations in 124 individuals using a standard UV/Vis microplate reader: a novel concept for mutation scanning
    Year: 2006
    Journal: Nucleic Acids Research
    Volume: 34
    Issue: 6
    Page numbers: e45
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  • Human Variome Project: an international collaboration to catalogue human genetic variation.
    Year: 2006
    Journal: Pharmacogenomics
    Volume: 7
    Issue: 7
    Page numbers: 969-72
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  • Human mutation databases
    Year: 2006
    Journal: Human Genomics
    Volume: 2
    Issue: 5
    Page numbers: 272
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  • Mutations causing inherited disease and cancer affect individuals and families
    Year: 2006
    Journal: Genetics in Medicine
    Volume: 8
    Issue: 6
    Page numbers: 389
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  • Reply to Dr. Strom regarding "A call for mutations"
    Year: 2006
    Journal: Genetics in Medicine
    Volume: 8
    Issue: 7
    Page numbers: 459
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  • Scanning the ocular albinism 1 (OA1)  gene for polymorphisms  in congenital nystagmus by DHPLC
    Year: 2006
    Journal: Ophthalmic Genetics
    Volume: 27
    Issue: 2
    Page numbers: 43-49
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  • Spontaneous DNA-DNA interaction of homologous duplexes and factors affecting the result of heteroduplax formation
    Year: 2006
    Journal: Biological Chemistry
    Volume: 387
    Issue: 3
    Page numbers: 257-261
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Publications in 2005

Book Chapters

  • Enzymatic and chemical cleavage methods to dientify genetic variation
    Year: 2005
    Book: Molecular diagnostics
    Publisher: Elsevier Science(Massachusetts)
    Authors(s):

Journal Articles

  • A call for mutations
    Year: 2005
    Journal: Genetics in Medicine
    Volume: 7
    Issue: 5
    Page numbers: 370
    Publisher: Lippincott Williams & Wilkins
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  • Locus-specific Databases: From Ethical Principles to Practice
    Year: 2005
    Journal: Human Mutation
    Volume: 26
    Page numbers: 489-493
    Publisher: Wiley-Liss(New York)
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  • Toward a Human Variome Project
    Year: 2005
    Journal: Human Mutation
    Volume: 26
    Page numbers: 499
    Publisher: Wiley-Liss(New York)
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Major Reference Works

  • Guide to Mutation Detection:Chemical Cleavage of Mismatch and Enzyme Mismatch Cleavage
    Year: 2005
    Reference Work Title: Guide to Mutation Detection
    Publisher: Wiley-Liss(New York)
    Author(s):
  • Guide to Mutation Detection:Enzymatic and Chemical Cleavage Methods
    Year: 2005
    Reference Work Title: Guide to Mutation Detection
    Publisher: Wiley-Liss(New York)
    Author(s):
  • Guide to Mutation Detection:Mutation Databases
    Year: 2005
    Reference Work Title: Guide to Mutation Detection
    Publisher: Wiley-Liss(New York)
    Author(s):

Publications in 2004

Journal Articles

  • Current chemicals used for probing DNA conformational changes and detection of unknown mutations
    Year: 2004
    Journal: Current Pharmacogenomics
    Volume: 2
    Issue: 4
    Page numbers: 325-332
    Publisher: Bentham Science Publishers(Hilversum)
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  • Expression of truncated presenilin 2 splice variant in Alzheimer's disease, bipolar disorder, and schizophrenia brain cortex
    Year: 2004
    Journal: Molecular Brain Research
    Volume: 127
    Issue: 1-2
    Page numbers: 128-135
    Publisher: Elsevier Science(Amsterdam)
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  • Novel TP53 gene mutations in tumors of Russian patients with breast cancer detected using a new solid phase chemical cleavage of mismatch method and identified by sequencing
    Year: 2004
    Journal: Human Mutation
    Volume: 23
    Page numbers: 186-192
    Publisher: Wiley-Liss(New York)
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  • The challenge of documenting mutation across the genome: the human genome variation society approach
    Year: 2004
    Journal: Human Mutation
    Volume: 23
    Page numbers: 447-452
    Publisher: Wiley-Liss(New York)
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  • The way station: the novel way for the collection of pancreatitis-associated mutations
    Year: 2004
    Journal: Pancreatology
    Volume: 4
    Page numbers: 249-250
    Publisher: S Karger AG(Basel)
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  • UV-visible spectral identification of the solution-phase and solid-phase permanganate oxidation reactions of thymine acetic acid
    Year: 2004
    Journal: Bioorganic and Medicinal Chemistry Letters
    Volume: 14
    Page numbers: 1313-1315
    Publisher: Pergamon-Elsevier Science(Oxford)
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Publications in 2003

Book Chapters

  • Human genome variation society
    Year: 2003
    Book: Human genome variation society
    Publisher: Macmillan Publishers(London)
    Authors(s):
  • Mutation databases and ethical considerations
    Year: 2003
    Book: Populations and genetics legal and socio-ethical perspectives
    Publisher: Brill Academic Publishers(Leiden)
    Authors(s):
  • Mutation detection
    Year: 2003
    Book: Nature encyclopedia of the human genome
    Publisher: Macmillan Publishers(London)
    Authors(s):
  • Sensitive and fast mutation detection by solid-phase chemical cleavage of mismatches
    Year: 2003
    Book: PCR Primer. A laboratory manual
    Publisher: Cold Spring Harbour Laboratory Press(New York)
    Authors(s):

Journal Articles

  • Chemical cleavage reactions of DNA on solid support: application in mutation detection
    Year: 2003
    Journal: BMC Chemical Biology
    Volume: 3
    Page numbers: 1-6
    Publisher: Biomed Central
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  • Mutations in the COL4A4 gene in thin basement membrane disease
    Year: 2003
    Journal: Kidney International
    Volume: 63
    Page numbers: 447-453
    Publisher: Blackwell Science(Massachusetts)
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  • Permanganate oxidation reactions of DNA: perspective in biological studies
    Year: 2003
    Journal: Nucleosides, Nucleotides and Nucleic Acids
    Volume: 22
    Issue: 9
    Page numbers: 1835-1855
    Publisher: Marcel Dekker(New York)
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  • Plastic contaminant masquerades as DNA in mutation detection by denaturing HPLC
    Year: 2003
    Journal: Biotechniques
    Volume: 34
    Issue: 1
    Page numbers: 59-60
    Publisher: Eaton Publishing Group(Massachusetts)
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  • Spectroscopic study of permanganate oxidation reactions of oligonucleotides containing single base mismatches
    Year: 2003
    Journal: Biopolymers
    Volume: 70
    Page numbers: 628-636
    Publisher: John Wiley & Sons(Hoboken)
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  • Variations of the human glucocorticoid receptor gene (NR3C1):pathological and in vitro mutations and polymorphisms
    Year: 2003
    Journal: Human Mutation
    Volume: 21
    Page numbers: 557-568
    Publisher: Wiley-Liss(New York)
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Publications in 2002

Book Chapters

  • Detection of mutations in DNA by solid-phase chemical cleavage method
    Year: 2002
    Book: Single nucleotide polymorphisms methods and protocols
    Publisher: Humana Press(New Jersey)
    Authors(s):

Journal Articles

  • Alternative transcripts of presenilin-I associated with frontotemporal dementia
    Year: 2002
    Journal: NeuroReport
    Volume: 13
    Issue: 5
    Page numbers: 917-921
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Comparative study of permanganate oxidation reactions of nucleotide bases by spectroscopy
    Year: 2002
    Journal: Bioorganic Chemistry
    Volume: 30
    Page numbers: 133-137
    Publisher: Academic Press - Elsevier Science
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  • Mutation detection 2001: novel technologies, developments and applications for analysis of the human genome
    Year: 2002
    Journal: Human Mutation
    Volume: 19
    Issue: 4
    Page numbers: 313-314
    Publisher: Wiley-Liss(New York)
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  • Site-selective reactions of imperfectly matched DNA with small chemical molecules: applications in mutation detection
    Year: 2002
    Journal: Bioorganic Chemistry
    Volume: 30
    Page numbers: 216-232
    Publisher: Academic Press - Elsevier Science
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  • The HUGO mutation database initiative
    Year: 2002
    Journal: The Pharmacogenomics Journal
    Volume: 2
    Page numbers: 16-19
    Publisher: Nature Publishing Group
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  • The human genome project and genome variation
    Year: 2002
    Journal: Internal Medicine Journal
    Volume: 32
    Page numbers: 285-288
    Publisher: Blackwell Science Asia(Carlton)
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  • Time for a unified system of mutation description and reporting: a review of locus-specific mutation databases
    Year: 2002
    Journal: Genome Research
    Volume: 12
    Page numbers: 680-688
    Publisher: Cold Spring Harbour Laboratory Press
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Publications in 2001

Journal Articles

  • COL4A4 mutation in thin basement membrane disease previously described in Alport syndrome.
    Year: 2001
    Journal: Kidney International
    Volume: 60
    Page numbers: 480-483
    Publisher: Blackwell Science(Massachusetts)
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  • Go!Poly: A gene-oriented polymorphism database
    Year: 2001
    Journal: Human Mutation
    Volume: 18
    Page numbers: 382-387
    Publisher: Wiley-Liss(New York)
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  • Interaction of linear homologous DNA duplexes via Holliday junction formation
    Year: 2001
    Journal: European Journal of Biochemistry
    Volume: 268
    Page numbers: 7-14
    Publisher: Blackwell Science(Oxford)
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  • Using CCM and DHPLC to detect mutations in the glucocorticoid receptor in atherosclerosis: a comparison.
    Year: 2001
    Journal: Journal of Biochemical and Biophysical Methods
    Volume: 47
    Page numbers: 91-100
    Publisher: Elsevier Science
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  • Variable phenotype of Alzheimer's disease with spastic paraparesis
    Year: 2001
    Journal: Annals of Neurology
    Volume: 49
    Issue: 1
    Page numbers: 125-129
    Publisher: Wiley-Liss(New York)
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