Contact Details
| Organization: | Pathology |
| Position: | Honorary (Fellow) |
| Email: | |
| Homepage: | http://www.path.unimelb.edu.au/research/labs/monagle/ |
| Work: | 834 43750 |
| Room: | W606 |
| Level: | 06 |
| Building: | Medical Centre |
| Campus: | Parkville |
Biography
Six years ago, I started working in my first research position as a Post Doctoral Scientist, and was responsible for setting up the Haematology Research Laboratory, in the Department of Clinical Haematology, at the Royal Children's Hospital (RCH), Melbourne. This time, required for setting up a research laboratory has had an impact on the number of my publications. However, my publication productivity has now improved significantly, as evidenced by five publications in 2007 alone.
In my current position, as the head of laboratory research in the Haematology Research Group, I play an integral role in our research activities. I am very excited to be working in translational research, as this allows me to see the application of the results of our studies into clinical practice. I have been intimately involved with the clinical diagnostic haematology laboratory at the RCH. Our work in developing age-appropriate reference ranges for coagulation parameters in children has been successfully translated into working reference ranges for the diagnostic laboratory at RCH. Globally, the results of this study are used as a reference point for many laboratories around the World. There is also considerable international interest in this data by regulatory groups concerned with quality management of paediatric coagulation laboratories.
In the past six years, I have worked on over twenty projects under the guidance and mentorship of Professor Paul Monagle (international clinical leader in the field of paediatric coagulation), who has been an invaluable contributor to my independence as a researcher. His clinical expertise combined with my research expertise, have resulted in a number of successful research projects, which in turn have provided a number of important publications for our research group.
My collaborative links as a researcher have expanded significantly and now include strong National (Australian Venom Research Unit; Pregnancy Research Centre; Department of Cardiology and Cardiac Surgery; Bio 21 Institute) and International (Henderson Research Centre, Hamilton, Canada; Medical University of Vienna, Austria) links.
In my role as the Head of the research laboratory, I have gained extensive experience in all aspects of running a research laboratory (administrative functions, preparing funding applications, setting-up new methods, training of research staff/students, database set-up, data analysis, manuscript preparation). In addition, my research experience has benefited significantly, through my role as a postgraduate student supervisor.
In my current position, as the head of laboratory research in the Haematology Research Group, I play an integral role in our research activities. I am very excited to be working in translational research, as this allows me to see the application of the results of our studies into clinical practice. I have been intimately involved with the clinical diagnostic haematology laboratory at the RCH. Our work in developing age-appropriate reference ranges for coagulation parameters in children has been successfully translated into working reference ranges for the diagnostic laboratory at RCH. Globally, the results of this study are used as a reference point for many laboratories around the World. There is also considerable international interest in this data by regulatory groups concerned with quality management of paediatric coagulation laboratories.
In the past six years, I have worked on over twenty projects under the guidance and mentorship of Professor Paul Monagle (international clinical leader in the field of paediatric coagulation), who has been an invaluable contributor to my independence as a researcher. His clinical expertise combined with my research expertise, have resulted in a number of successful research projects, which in turn have provided a number of important publications for our research group.
My collaborative links as a researcher have expanded significantly and now include strong National (Australian Venom Research Unit; Pregnancy Research Centre; Department of Cardiology and Cardiac Surgery; Bio 21 Institute) and International (Henderson Research Centre, Hamilton, Canada; Medical University of Vienna, Austria) links.
In my role as the Head of the research laboratory, I have gained extensive experience in all aspects of running a research laboratory (administrative functions, preparing funding applications, setting-up new methods, training of research staff/students, database set-up, data analysis, manuscript preparation). In addition, my research experience has benefited significantly, through my role as a postgraduate student supervisor.
Research Expertise and International Linkages
Research Expertise
| Research Interest | Country of Expertise |
|---|---|
| Paediatric and Perinatal Thrombosis and Haemostasis | Australia |
| Developmental Haemostasis | Australia |
International Linkages
| Country | Establishment | Collaboration |
|---|---|---|
| Canada | McMaster University | Exchange, Research, Technical Assistance/Training |
| Austria | University of Vienna | Exchange, Research, Technical Assistance/Training |
Qualifications, Honours, Fellowships and Other Awards
Qualifications
| Title | Institution | Date Awarded | Abbreviation |
|---|---|---|---|
| Bachelor of Science (Hons) | Monash University | 31-Dec-1996 | |
| Doctor of Philosophy (Medicine) | Monash University | 31-Dec-2000 |
Other Awards
| Award Type | Awarding Body | Comments | Date Awarded |
|---|---|---|---|
| Other (Award) | Young Investigator Award - International Society on Thrombosis and Haemostasis | 07-Jul-2007 | |
| Other (Award) | 2001 Travelling Fellowship - Paediatric Research Society of Australia and New Zealand. | 03-Sep-2001 | |
| Scholarship | Royal Children's Hospital Travelling Scholarship | 01-Jan-2003 | |
| Prize | HSANZ - Travelling Grant | 01-Jan-2003 |
Government Research Classifications
Research Fields, Courses and Discipline Classifications
- Biochemistry and Cell Biology not elsewhere classified (BIOCHEMISTRY AND CELL BIOLOGY) (270199)
- Pathology (VETERINARY SCIENCES) (300506)
- Clinical Chemistry (MEDICAL BIOCHEMISTRY AND CLINICAL CHEMISTRY) (320301)
- Basic Pharmacology (PHARMACOLOGY AND PHARMACEUTICAL SCIENCES) (320502)
- Toxicology (incl. Clinical Toxicology) (PHARMACOLOGY AND PHARMACEUTICAL SCIENCES) (320504)
- Pharmacology not elsewhere classified (PHARMACOLOGY AND PHARMACEUTICAL SCIENCES) (320599)
- Haematology (CLINICAL SCIENCES) (321008)
- Paediatrics (CLINICAL SCIENCES) (321019)
Socio-Economic Objective Classifications
- Treatments (e.g. chemicals, anntibiotics) (HUMAN PHARMACEUTICAL PRODUCTS) (670403)
- Blood disorders (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730103)
- Skeletal system and disorders (incl. Arthritis) (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730114)
- Clin health not spec to partlar organs, diseases & condits (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730199)
- Child health (PUBLIC HEALTH) (730204)
- Biological sciences (NON-ORIENTED RESEARCH) (780105)
Grants and Contracts
Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.
Grants
| Title | Role | Funding Source | Scheme | Award Date |
|---|---|---|---|---|
| Age-related response to heparin in children. | Chief Investigator | NHMRC | Project Grants | 01/01/2007 |
Contracts
| Title | Role | Funding Source | Award Date |
|---|---|---|---|
| PAEDIATRIC AND PERINATAL THROMBOSIS AND HAEMOSTASIS | Chief Investigator | UNIVERSITY OF CALIFORNIA | 01/07/2007 |
Additional Grant and Contract Information
GRANTS AWARDED2007 Murdoch Children’s Research Institute: Age-related structural and functional differences in haemostatic proteins. $25,000
Medical Research Grant: Gradient PCR machine purchase. $20,000
2007-9 NHMRC Project Grant: The impact of developmental haemostasis on the pharmacokinetics and pharmacodynamics of heparin in children. $273,000
2005-6 RAGS and NHMRS Equipment Grants: Gel Documentation and Analysis system (Syngene G:BOX). $61,475
Roche Diagnostics: CoaguChek XS study. $26,796
Murdoch Childrens Research Institute: Thrombin generation to assess bleeding and clotting risk in children. $43,000
Haemophilia Foundation Australia: Thrombin generation, the role of hyperfibrinolysis (levels of Thrombin Activatable Fibrinolysis Inhibitor; TAFI) and
levels of Tissue Factor Pathway Inhibitor (TFPI) in children with severe Haemophilia: correlation to clinical outcomes. $15,080
RAGS and NHMRC Equipment Grants: Platelet function studies in children: the impact of developmental haemostasis, toxic venoms and
Cardiopulmonary Bypass (CPB). $38,000
2004 University of Melbourne Award for Joint Research Projects: Analysis of the venom and medical importance of lesser known Australian snakes. $15,000
2002 Bayer Diagnostics: RapidPoint, point of care monitoring in children. $70,000
Publications
Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.