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MR ALEXANDER HEWITT



Contact Details

Organization: Ophthalmology Eye and Ear Hospital
Position: Honorary (Fellow)
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Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Quantitative genetic analysis of the retinal vascular caliber: the Australian twins eye study


    Year: 2009
    Journal: Hypertension
    Volume: 54
    Issue: 4
    Page numbers: 788-795
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  • A systematic meta-analysis of genetic association studies for diabetic retinopathy
    Year: 2009
    Journal: Diabetes
    Volume: 58
    Issue: 9
    Page numbers: 2137-2147
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  • Birth factors and retinal vascular caliber in a twin study. Response
    Year: 2009
    Journal: Hypertension
    Volume: 53
    Issue: 4
    Page numbers: E29-E30
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  • Effect of birth parameters on retinal vascular caliber: the twins eye study in Tasmania
    Year: 2009
    Journal: Hypertension
    Volume: 53
    Issue: 3
    Page numbers: 487-493
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  • Genetic influences on handedness: Data from 25,732 Australian and Dutch twin families
    Year: 2009
    Journal: Neuropsychologia
    Volume: 47
    Issue: 2
    Page numbers: 330-337
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  • Identification of LOXL1 protein and Apolipoprotein E as components of surgically isolated pseudoexfoliation material by direct mass spectrometry
    Year: 2009
    Journal: Experimental Eye Research
    Volume: 89
    Issue: 4
    Page numbers: 479-485
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  • Optic disc morphology - Rethinking shape
    Year: 2009
    Journal: Progress in Retinal and Eye Research
    Volume: 28
    Issue: 4
    Page numbers: 227-248
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  • Primary open angle glaucoma in subjects harbouring the predicted GLC1L haplotype reveals a normotensive phenotype
    Year: 2009
    Journal: Clinical and Experimental Ophthalmology
    Volume: 37
    Issue: 2
    Page numbers: 201-207
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  • Rapid inexpensive genome-wide association using pooled whole blood
    Year: 2009
    Journal: Genome Research
    Volume: 19
    Issue: 11
    Page numbers: 2075-2080
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  • Twins eye study in Tasmania (TEST): rationale and methodology to recruit and examine twins
    Year: 2009
    Journal: Twin Research and Human Genetics
    Volume: 12
    Issue: 5
    Page numbers: 441-454
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Publications in 2008

Journal Articles

  • Ancestral LOXL1 variants are associated with pseudoexfoliation in Caucasian Australians but with markedly lower penetrance than in Nordic people
    Year: 2008
    Journal: Human Molecular Genetics
    Volume: 17
    Issue: 5
    Page numbers: 710-716
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  • Genetic analysis of the clusterin gene in pseudoexfoliation syndrome
    Year: 2008
    Journal: Molecular Vision
    Volume: 14
    Page numbers: 1727-1736
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  • Genetic dissection of myopia: evidence for linkage of ocular axial length to chromosome 5q
    Year: 2008
    Journal: Ophthalmology
    Volume: 115
    Issue: 6
    Page numbers: 1053-1057
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  • Genetic isolates in ophthalmic disease
    Year: 2008
    Journal: Ophthalmic Genetics
    Volume: 29
    Issue: 4
    Page numbers: 149-161
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  • Heritability of the iridotrabecular angle width measured by optical coherence tomography in Chinese children: the Guangzhou twin eye study
    Year: 2008
    Journal: Investigative Ophthalmology and Visual Science
    Volume: 49
    Issue: 4
    Page numbers: 1356-1361
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  • Myocilin allele-specific glaucoma phenotype database
    Year: 2008
    Journal: Human Mutation
    Volume: 29
    Issue: 2
    Page numbers: 207-211
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  • The natural history of OPA1-related autosomal dominant optic atrophy
    Year: 2008
    Journal: British Journal of Ophthalmology
    Volume: 92
    Issue: 10
    Page numbers: 1333-1336
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Publications in 2007

Journal Articles

  • Screening for glaucomatous disc changes prior to diagnosis of glaucoma in myocilin pedigrees.


    Year: 2007
    Journal: Archives of Ophthalmology
    Volume: 125
    Issue: 1
    Page numbers: 112-116
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  • Autosomal dominant optic atrophy:  penetrance and expressivity in patients with OPA1 mutations.
    Year: 2007
    Journal: American Journal of Ophthalmology
    Volume: 143
    Issue: 4
    Page numbers: 656-662
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  • Heritable features of the optic disc:  A novel twin method for determining genetic significance.
    Year: 2007
    Journal: Investigative Ophthalmology and Visual Science
    Volume: 48
    Issue: 6
    Page numbers: 2469-2475
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  • Myocilin Gly252Arg mutation and glaucoma of intermediate severity in caucasian individuals.
    Year: 2007
    Journal: Archives of Ophthalmology
    Volume: 125
    Issue: 1
    Page numbers: 98-104
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  • PAX6 mutations may be associated with high myopia
    Year: 2007
    Journal: Ophthalmic Genetics
    Volume: 28
    Issue: 3
    Page numbers: 179-182
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  • Prevalence of CYP1B1 mutations in Australian patients with primary congenital glaucoma
    Year: 2007
    Journal: Clinical Genetics
    Volume: 72
    Issue: 3
    Page numbers: 255-260
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  • The optic nerve head in Myocilin glaucoma.
    Year: 2007
    Journal: Investigative Ophthalmology and Visual Science
    Volume: 48
    Issue: 1
    Page numbers: 238-243
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Publications in 2006

Journal Articles

  • A Myocilin Gln368STOP homozygote does not exhibit a more severe glaucoma phenotype than heterozygous cases.
    Year: 2006
    Journal: American Journal of Ophthalmology
    Volume: 141
    Issue: 2
    Page numbers: 402-403
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  • A glaucoma case-control study of the WDR36 gene D658G sequence variant.
    Year: 2006
    Journal: American Journal of Ophthalmology
    Volume: 142
    Issue: 2
    Page numbers: 324-325
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  • Complex genetics of complex traits:  the case of primary open-angle glaucoma.
    Year: 2006
    Journal: Clinical and Experimental Ophthalmology
    Volume: 34
    Issue: 5
    Page numbers: 472-484
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  • Disease severity of familial glaucoma compared with sporadic glaucoma.
    Year: 2006
    Journal: Archives of Ophthalmology
    Volume: 124
    Issue: 7
    Page numbers: 950-954
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  • Familial transmission risks of infantile glaucoma in Australia.
    Year: 2006
    Journal: Ophthalmic Genetics
    Volume: 27
    Issue: 3
    Page numbers: 93-97
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  • The role of the Met98Lys optineurin variant in inherited optic nerve diseases.
    Year: 2006
    Journal: British Journal of Ophthalmology
    Volume: 90
    Issue: 11
    Page numbers: 1420-1424
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  • Tools for cup:disc ratio measurement
    Year: 2006
    Journal: Clinical and Experimental Ophthalmology
    Volume: 34
    Issue: 3
    Page numbers: 288-9
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Publications in 2005

Journal Articles

  • Central Corneal Thickness Is Highly Heritable: The Twin Eye Studies
    Year: 2005
    Journal: Investigative Ophthalmology and Visual Science
    Volume: 46
    Issue: 10
    Page numbers: 3718-3722
    Publisher: Association for Research in Vision and Ophthalmology Inc(Maryland)
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  • Genotypic and phenotypic spectrum of X-linked retinoschisis in Australia
    Year: 2005
    Journal: Clinical and Experimental Ophthalmology
    Volume: 33
    Page numbers: 233-239
    Publisher: Blackwell Science Asia(Carlton)
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  • Lack of association of p53 polymorphisms and hapiotypes in high and normal tension open angle glaucoma
    Year: 2005
    Journal: Journal of Medical Genetics
    Volume: 42
    Page numbers: 1-4
    Publisher: BMJ Publishing Group(London)
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