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PROF DAVID DUNSTAN



Contact Details

Organization: Chemical and Biomolecular Engineering
Position: PROFESSOR
Email:
Homepage: www.chemeng.unimelb.edu.au/people/index.html
Work: 83448261
Fax: 83444153
Room: 3.24
Level: 03
Building: Chemical Engineering #1
Campus: Parkville

Biography

BRIEF DESCRIPTION OF CURRENT RESEARCH ACTIVITIES

  • Nano and Biomolecular Engineering
  • Nanostructured Materials - Light emitting polymers - Polymer dynamics
  • Microfluidics - Rheofluorescence
  • Biophysics - Drug delivery
  • Protein aggregation - Disease - Processing
  • Ceramic Materials

Member of the Particulate Fluids Processing Centre

OTHER ACTIVITIES:

  • Assistant Dean of Transition & Diversity for the Faculty of Engineering

COLLABORATIVE INTERACTIONS:

  • St Vincents Hospital
  • Centre for Blood Diseases, Monash Medical Centre
  • Victorian Pharmacy College, (Monash) Dr Ian Larson 
  • Bio21 and Department of Biochemistry 
  • Gelcast:  Portland Ceramics
  • CSL Bioplasma  
  • CSL Vaccines     
  • CSIRO Molecular Sciences 
  • Murdoch Children's Research Institute
  • Chemistry School, The University of Melbourne  

CONSULTING AND INDUSTRIAL INTERACTION:

  • CSL limited, Research and Development, Parkville
  • CSL limited, Bioplasma, Broadmeadows
  • Microns to Measure
  • Betz Dearborn
  • Goodman Fielder, Ingredients, Australia and US
  • Bonlac
  • Murray Goulburn
  • SC Johnson Wax
  • Carlton and United Breweries
  • Mobil
  • Clover Corporation
  • Unilever UK
  • Rhodia International, Australia and US
  • Uncle Ben’s Australia
  • Uncle Toby’s
  • Kraft
  • Kodak
  • Cerebos
  • Bureau of Sugar Experiment Stations

PATENTS:

  • 2 Patents
  • 3 Provisional Patents

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
Biophysics Australia
Rheology / Rheofluorescence Australia
Light Scattering Australia
Condensed Matter Physics Australia
Advanced Ceramics Australia
Biophysics of Protein Conformation Australia
Polymer Dynamics in Flow Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science University of Melbourne 05-Dec-1982
Doctor of Philosophy University of Melbourne 01-Sep-1989

Memberships

Membership Type Membership Body Description Start Date End Date
Member International Journal of Food Science and Technology Member of Editorial Board 10-Jul-1998
Member American Chemical Society Professional Affiliation 01-Jan-1993
Member American Institute of Physics Professional Affiliation 01-Jan-1996
Member American Society of Rheology Professional Affiliation 01-Jan-1993
Member New York Academy of Sciences Professional Affiliation 01-Jan-1989
Member Australian Society of Rheology Professional Affiliation 01-Jun-1993
Member Australian Society of Biotechnolgy Professional Affiliation 01-Jun-1991
Member International Hydrocolloids Trust Committee Member & Editorial Board Member 01-Jun-1998
Member American Association for the Advancement of Science Professional Affiliation 01-Jan-2000
Member Carbohydrate Polymers Member of Editorial Board 01-Jun-2001

Other Awards

Award Type Awarding Body Comments Date Awarded
Prize Melbourne University Grimwade Prize for Industrial Chemistry, Faculty of Science 01-Jul-2002

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Characterisation and stability of ISCOM vaccines Chief Investigator AUST RESEARCH COUNCIL Linkage Projects 01/01/2002
Spectroscopy of complex fluids in flow Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2003
Materials and surface characterisation facility Chief Investigator AUST RESEARCH COUNCIL Linkage Infrastructure (Equipment and Facilities) 01/01/2005
MULTI-FUNCTIONAL FLUORESCENCE MICROSCOPY LABORATORY Chief Investigator RMIT Linkage Projects (AUST RESEARCH COUNCIL) 01/01/2005
PROCESS INDUCED PROTEIN AGGREGATION Chief Investigator AUST RESEARCH COUNCIL,
CSL BIOPLASMA
Linkage Projects (AUST RESEARCH COUNCIL) 01/01/2006
Towards Nano-Assembled Light Emitting Polymer Films Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2006
The Melbourne Nanofabrication Facility Chief Investigator AUST RESEARCH COUNCIL Linkage Infrastructure (Equipment and Facilities) 01/01/2007
Nanomaterials Optical Characterisation Facility Chief Investigator MONASH UNIVERSITY,
SWINBURNE UNIVERSITY,
AUST RESEARCH COUNCIL
Linkage Infrastructure (Equipment and Facilities) (AUST RESEARCH COUNCIL) 01/01/2007
Development of a fibre-optic flow sensor to monitor blood platelet adhesive function Chief Investigator MONASH UNIVERSITY Development Grants (NHMRC) 01/01/2007
Macromolecular Self-Assembly of Amyloid Fibrils Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2008
POLYMER CHARACTERISATION FACILITY (PCF) Chief Investigator AUST RESEARCH COUNCIL Linkage Infrastructure (Equipment and Facilities) 01/01/2008
Advanced NanoBiomaterials Imaging Facility Chief Investigator AUST RESEARCH COUNCIL Linkage Infrastructure (Equipment and Facilities) 01/01/2009

Contracts

Title Role Funding Source Award Date
CRC FOR BIOPRODUCTS - BIOPRODUCT APPLICATIONS Chief Investigator CRC FOR BIOPRODUCTS 01/07/1999
DIGA DUNSTAN 05/07 - DYNAMIC LIGHT SCATTERING - PHYSICO-CHEMICAL STUDIES OF MILK POWDER REHYDRATION Chief Investigator DAIRY INNOVATION AUSTRALIA LTD 01/06/2005
STRUCTURE CREATION IN FLOW OF BIOPOLYMER FLUID GELS Chief Investigator UNILEVER NEDERLAND BV

Additional Grant and Contract Information

FURTHER GRANT DETAILS:

  • 2002   ARC Linkage Infrastructure, Equipment and Facilities Grant: $1.83M
  • 2002   ARC Linkage Grant: Characterisation of ISCOM Vaccines, with CSL Limited 2005 To examine and correlate the immunogenicity with the physical characteristics of ISCOM vaccines. Total grant $289,000 over three years
  • 2003   ARC Discovery Grant with Derek Chan: Spectroscopy of Polymers in Flow, 2005 $433,000
  • 2003   ARC LEIF Grant: Integrated Facility for Interfacial Rheology. $250,000
  • 2005   ARC Discovery Grant with Trevor Smith and John Sader, Towards nano- assembled light emitting polymer films $345,000
  • 2005   ARC LEIF Grant: Materials and Surface Characterisation Facility. $1.6M
  • 2005   ARC Linkage Grant: Process induced Protein Aggregation, Industry Partner CSL Bioplasma. Total grant $245,000 over 3 years
  • 2005   ARC LEIF Grant: Melbourne Nanofabrication Facility. $800,000.
  • 2005   Unilever Structure and Rheology of Fluid Gels $135,000.
  • 2005   Dairy Ingredients Group Australia, Rehydration of Milk Powders, $120,000
  • 2005   ARC LEIF Grant: Multi-Functional Fluorescence Microscopy Facility. $150,000
  • 2006   Contribution as Program II Leader to the renewal of the CRC for Bioproducts, $13.7M over seven years, as a member of the Executive Committee and Program Leader. Of the total grant received, Aus. $284,000 p.a. is allocated to the Department of Chemical Engineering, with $600,000 p.a. allocated to program 2
  • 2007   NH&MRC Development Grant with Professor Shaun Jackson (Monash) “ Development of Rapid Diagnostic Methods for Blood Platelet Activity” $183,000
  • 2007   ARC LEIF Grant: “Polymer Characterisation Facility”, With Frank Caruso et al, $588,000
  • 2007   ARC Discovery Grant “Macromolecular Self Assembly of Amyloid Fibrils” William Ducker, Geoff Howlett and Dave E. Dunstan $428,000 / 3 years 
  • 2007   Application: NH&MRC Program Grant “Understanding the Mechanisms Underlying the Therapeutic Potential of PEDF in Osteosarcoma. Peter Choong, David Thomas, Crispin Dass and Dave E. Dunstan.
  • 2007   Application: FAST Program Grant "Structured Fluids Using Polysaccharide Surfactant Complexes" with Denis Roux, Domaine University, Grenoble, France.

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Conformational Changes and Photophysical Behavior in Poly[2-methoxy-5-(2'-ethyl-hexyloxy)-1,4-phenylene vinylene] Thin Films Cast under an Electric Field
    Year: 2009
    Journal: Journal of Physical Chemistry C
    Volume: 113
    Page numbers: 11657�11661
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Publications in 2008

Journal Articles

  • Cross-linked Polyvinyl Alcohol as a Binder for Gelcasting and Green Machining


    Year: 2008
    Journal: Journal of the American Ceramic Society
    Volume: 91
    Issue: 10
    Page numbers: 3138-3146
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  • Adhesion measurements between alginate gel surfaces via texture analysis
    Year: 2008
    Journal: Food Hydrocolloids
    Volume: 22
    Issue: 1
    Page numbers: 91-96
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  • Biocompatible chitosan-DNAzyme nanoparticle exhibits enhanced biological activity
    Year: 2008
    Journal: Journal of Microencapsulation
    Volume: 25
    Issue: 6
    Page numbers: 421 - 425
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  • Comparison of rennet gelation using raw and reconstituted skim milk
    Year: 2008
    Journal: International Dairy Journal
    Volume: 18
    Page numbers: 1077-1080
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  • Cross-linked Polyvinyl Alcohol as a Binder for Gelcasting and Green Machining
    Year: 2008
    Journal: Journal of the American Ceramic Society
    Volume: 91
    Issue: 10
    Page numbers: 3138-3146
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  • Downregulation of c-jun results in apoptosis-mediated anti-osteosarcoma activity in an orthotopic model
    Year: 2008
    Journal: Cancer Biology & Therapy
    Volume: 7
    Issue: 7
    Page numbers: 1033-1036
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  • How Does Shear Affect A# Fibrillogenesis?
    Year: 2008
    Journal: Journal of Physical Chemistry B
    Volume: 112
    Issue: 51
    Page numbers: 16249-16252
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  • Injectable chitosan hydrogels for localised cancer therapy
    Year: 2008
    Journal: Journal of Controlled Release
    Volume: 126
    Issue: 3
    Page numbers: 205-216
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  • Measurement of the optical properties and shape of nanoparticles in solution using Couette flow
    Year: 2008
    Journal: ACS Nano
    Volume: 2
    Issue: 2
    Page numbers: 334-340
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  • Rubber bands as model polymers in couette flow
    Year: 2008
    Journal: European Journal of Physics
    Volume: 29
    Page numbers: 977-985
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  • Stress and Strain Controlled Rheometry on a Concentrated Iyotropic Lamellar Phase of AOT/Water/Iso-octane
    Year: 2008
    Journal: Rheologica Acta
    Volume: 1
    Issue: 1
    Page numbers: 1-9
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Publications in 2007

Journal Articles

  • Soluble manganese (IV) as a chemiluminescence reagent for the determination of opiate alkaloids, indoles and analytes of forensic interest


    Year: 2007
    Journal: Talanta
    Volume: 71
    Issue: 5
    Page numbers: 1951-1957
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  • Avoiding "mud" cracks during drying of thin films from aqueous colloidal suspensions
    Year: 2007
    Journal: Journal of Colloid and Interface Science
    Volume: 313
    Issue: 1
    Page numbers: 160-168
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  • Chitosan microparticles encapsulating PEDF plasmid demonstrate efficacy in an orthotopic metastatic model of osteosarcoma
    Year: 2007
    Journal: Biomaterials
    Volume: 28
    Issue: 19
    Page numbers: 3026-33
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  • Comparison of Casein Micelles in Raw and Reconstituted Skim Milk
    Year: 2007
    Journal: Journal of Dairy Science
    Volume: 90
    Issue: 10
    Page numbers: 4543-4551
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  • Compressive elasticity in polymer Couette flow
    Year: 2007
    Journal: European Physical Journal - Applied Physics
    Volume: 38
    Issue: 1
    Page numbers: 93-95
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  • Infiltration of Macromolecules into Nanoporous Silica Particles
    Year: 2007
    Journal: Macromolecules
    Volume: 40
    Page numbers: 7594-7600
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  • Terraced self assembled nano-structures from laminarin
    Year: 2007
    Journal: International Journal of Biological Macromolecules
    Volume: 40
    Issue: 4
    Page numbers: 362-366
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  • Tris (2,2 '-bipyridyl) ruthenium(II) chemiluminescence enhanced by silver nanoparticles
    Year: 2007
    Journal: Chemical Communications
    Volume: 4
    Issue: 10
    Page numbers: 395-397
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Publications in 2006

Journal Articles

  • Shear flow induces amyloid fibril formation
    Year: 2006
    Journal: Biomacromolecules
    Volume: 7
    Issue: 1
    Page numbers: 10-13
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  • The 7th International Hydrocolloids Conference August 29-September 1, 2004
    Year: 2006
    Journal: Food Hydrocolloids
    Volume: 20
    Issue: 2-3
    Page numbers: 145
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Conference Publications/Papers

  • Novel aqueous tape casting process
    Year: 2006
    Event name: 107th Annual Meeting of the American Ceramic Society
    Conference Publication: Proceedings of the 107th Annual Meeting of the American Ceramic Society
    Publisher: Wiley Press(New York)
    Author(s):
    Editor(s):
    URL - restricted access http://www.wiley.com/WileyCDA/WileyTitle/productCd-157498

Publications in 2005

Journal Articles

  • Rheofluorescence studies of poly(p-phenylenevinylene) derivatives in simple shear flow
    Year: 2005
    Journal: Synthetic Metals
    Volume: 153
    Page numbers: 213-216
    Publisher: Elsevier Science(Lausanne)
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  • Rheofluorescence technique for the study of dilute MEH-PPV solutions in couette flow
    Year: 2005
    Journal: Journal of Fluorescence
    Volume: 15
    Issue: 3
    Page numbers: 255-267
    Publisher: Plenum Publishing Corp(New York)
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  • Shear Flow Induces Amyloid Fibril Formation
    Year: 2005
    Journal: Biomacromolecules
    Volume: 7
    Page numbers: 10-13
    Publisher: American Chemical Society(Washington)
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  • The 7th International Hydrocolloids Conference, August 29 - September 1, 2004
    Year: 2005
    Journal: Food Hydrocolloids
    Volume: 20
    Issue: 2-3
    Page numbers: 145-402
    Publisher: Elsevier Science(Oxford)
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Conference Publications/Papers

  • Strong through to weak sheared gels
    Year: 2005
    Event name: The Society of Rheology: 77th Annual Meeting
    Conference Publication: Society of Rheology 77th Annual Meeting
    Volume: 1
    Page numbers: 29-30
    Publisher: Albert Co(Maine)
    Author(s):

Publications in 2004

Journal Articles

  • A novel thermally-activated crosslinking agent for chitosan in aqueous solution: a rheological investigation
    Year: 2004
    Journal: Colloid and Polymer Science
    Volume: 282
    Issue: 6
    Page numbers: 602-612
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  • Direct measurement of polydiacetylene 4-butoxycarbonylmethylurethane segment orientation and distortion in shear: Semi-dilute solutions
    Year: 2004
    Journal: Macromolecules
    Volume: 37
    Issue: 4
    Page numbers: 1663-1665
    Publisher: American Chemical Society(Washington DC)
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  • Direct measurement of polymer segment orientation and distortion in shear: Semi-dilute solution behaviour
    Year: 2004
    Journal: Polymer
    Volume: 45
    Issue: 4
    Page numbers: 1261-1266
    Publisher: Elsevier Science(Oxford)
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  • Probing drug solubilization patterns in the gastrointestinal tract after administration of lipid-based delivery systems: A phase diagram approach
    Year: 2004
    Journal: Journal of Pharmaceutical Sciences
    Volume: 93
    Issue: 2
    Page numbers: 332-348
    Publisher: John Wiley & Sons(New York)
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  • Strong through to weak 'sheared' gels
    Year: 2004
    Journal: Journal of Non-Newtonian Fluid Mechanics
    Volume: 124
    Issue: 1-3
    Page numbers: 129-136
    Publisher: Elsevier Science(Amsterdam)
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Conference Publications/Papers

  • Characterisation of pectin gelation using 8-anilino-1-naphthalene-sulphonic acid as a fluorescent probe
    Year: 2004
    Event name: Wrexham 2003:Gums and Stabilisers for the food industry 12
    Conference Publication: Gums and Stabilisers for the Food Industry 12
    Page numbers: 354-359
    Publisher: RSC Press(Cambridge)
    Author(s):
  • Direct measurement of polymer segment orientation and distortion in shear: Semi-dilute solution behaviour of a conjugated system
    Year: 2004
    Event name: Third International Symposium on Slow Dynamics in Complex Systems
    Conference Publication: AIP Conference Proceedings 708 (Slow Synamics in Complex Systems)
    Page numbers: 209-212
    Publisher: American Institute of Physics(New York)
    Author(s):
  • Fluorescence spectroscopy of poly(p-phenylenevinylene) derivatives in flow
    Year: 2004
    Event name: International Conference on Synthetic Metals 2004
    Conference Publication: Conference Proceedings, ICSM 2004
    Page numbers: 42-45
    Publisher: Intelligent Polymer Research Institute, University of Wollongong(Wollongong)
    Author(s):

Publications in 2003

Publications in 2002

Book Chapters

  • Determining the yield stress of Xanthan solutions via droplet rise experiments
    Year: 2002
    Book: Gums and Stabilisers for the Food Industry 11: Special publication No. 278
    Publisher: Royal Society of Chemistry(Cambridge)
    Authors(s):
    Editors(s):

Journal Articles

  • Control over PEGylated-liposome aggregation by NeutrAvidin-Biotin interactions investigated by photon correlation spectroscopy
    Year: 2002
    Journal: Langmuir
    Volume: 18
    Page numbers: 505-511
    Publisher: American Chemical Society(Washington DC)
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  • Fluorescence polarization measurements of the local viscosity of hydroxypropyl guar in solution
    Year: 2002
    Journal: Macromolecules
    Volume: 35
    Page numbers: 2736-2742
    Publisher: American Chemical Society(Washington DC)
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  • Particulate hematite diffusion in sodium polyacrylate solutions. The effect of ionic strength
    Year: 2002
    Journal: Journal of Colloid and Interface Science
    Volume: 247
    Issue: 2
    Page numbers: 303-309
    Author(s):
    URL - restricted access http://dx.doi.org/10.1006/jcis.201.8150
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  • Probe diffusion measurements of polystyrene latex particles in polyelectrolyte solutions of varying ionic strength
    Year: 2002
    Journal: Macromolecules
    Volume: 35
    Page numbers: 1994-1999
    Publisher: American Chemical Society(Washington DC)
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  • Rheology of cross-linked chitosan-alumina suspensions used for a new gelcasting process
    Year: 2002
    Journal: Journal of the American Ceramic Society
    Volume: 85
    Page numbers: 1699-1705
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  • The central domain of Escherichia coli TyrR is responsible for hexamerization associated with tyrosine-mediated repression of gene expression
    Year: 2002
    Journal: Journal of Biological Chemistry
    Volume: 277
    Issue: 26
    Page numbers: 23186-23192
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • The rheology of K+ -k-carrageenan as a weak gel
    Year: 2002
    Journal: Carbohydrate Polymers
    Volume: 50
    Page numbers: 109-116
    Publisher: Elsevier Science(Oxford)
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Conference Publications/Papers

  • Fluorescence anisotropy measurements of the dynamic behaviour of biopolymers
    Year: 2002
    Event name: The Eleventh Gums and Stabilisers for the Food Industry Conference
    Conference Publication: Gums and stabilisers for the food industry 11
    Page numbers: 54-64
    Publisher: Royal Society of Chemistry(Cambridge)
    Author(s):
  • Time resolved polarised attenuated total reflection spectroscopy of a protein film at the silica/solution interface
    Year: 2002
    Event name: 6th World Congress of Chemical Engineering
    Conference Publication: Proceedings of the 6th World Congress of Chemical Engineering
    Volume: 1
    Page numbers: 10
    Publisher: Institute of Chemical Engineers Australia(Melbourne)
    Author(s):
  • Time-resolved polarised attenuated total reflection spectroscopy of a protein film at the silica/solution interface
    Year: 2002
    Event name: Gums and Stabilisers for the Food Industry
    Conference Publication: Gums and Stabilisers in the Food Industry II
    Volume: 278
    Page numbers: 65-72
    Publisher: Royal Society of Chemistry(Cambridge)
    Author(s):

Publications in 2001

Book Chapters

  • Gelforming of advanced ceramic components with the biopolymer chitosan
    Year: 2001
    Book: Ceramic Processing Science VI
    Publisher: American Ceramic Society(Westerville)
    Authors(s):
    Editors(s):

Journal Articles

  • Diffusing probe measurements in Newtonian and elastic solutions


    Year: 2001
    Journal: Advances in Colloid and Interface Science
    Volume: 89-90
    Issue: 1
    Page numbers: 141-154
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  • A spectroscopic study of polyelectrolyte solutions under shear
    Year: 2001
    Journal: Polymer
    Volume: 42
    Page numbers: 6981-6989
    Publisher: Elsevier Science(Oxford)
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  • Atomic force microscopy imaging of DNA-cationic liposome complexes optimised for gene transfection into neuronal cells.
    Year: 2001
    Journal: Journal of Gene Medicine
    Volume: 3
    Issue: 1
    Page numbers: 72-81
    Publisher: John Wiley & Sons(West Sussex)
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  • Dependence of linear viscoelastic critical strain and stress values on extent of gelation for a thermally activated gelling system
    Year: 2001
    Journal: Rheologica Acta
    Volume: 40
    Page numbers: 23-29
    Publisher: Springer Verlag(New York)
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  • Gel point studies for chemically modified biopolymer networks using small amplitude oscillatory rheometry
    Year: 2001
    Journal: Polymer
    Volume: 42
    Page numbers: 185-198
    Publisher: Elsevier Science(Oxford)
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  • Heterodyne and nonergodic approach to dynamic light scattering of polymer gels: Aqueous xanthan in the presence of metal ions (Aluminium (III))
    Year: 2001
    Journal: Macromolecules
    Volume: 34
    Page numbers: 3339-3352
    Publisher: American Chemical Society(Washington DC)
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  • Polymer concentration dependence of the gel point for chemically modified biopolymer networks using small amplitude oscillatory rheometry
    Year: 2001
    Journal: Polymer
    Volume: 42
    Page numbers: 3923-3928
    Publisher: Elsevier Science(Oxford)
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  • Predictions of the change in extinction coefficient for prolate particles
    Year: 2001
    Journal: Journal of Chemical Physics
    Volume: 115
    Issue: 12
    Page numbers: 5679-5689
    Publisher: American Institute of Physics(New York)
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  • Rheo-optics of a conjugated polymer system in shear
    Year: 2001
    Journal: Polymer
    Volume: 42
    Issue: 18
    Page numbers: 7755-7764
    Publisher: Elsevier Science(Oxford)
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  • Rheological characterisation of k-carrageenan/locust bean gum mixtures
    Year: 2001
    Journal: Carbohydrate Polymers
    Volume: 46
    Page numbers: 117-124
    Publisher: Elsevier Science(Oxford)
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  • Rheology of Dextran Solutions
    Year: 2001
    Journal: Journal of Non-Newtonian Fluid Mechanics
    Volume: 97
    Issue: 2/3
    Page numbers: 295-301
    Publisher: Elsevier Science(Amsterdam)
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  • Structure and rheology of the k-carrageenan/locust bean gum gels
    Year: 2001
    Journal: Food Hydrocolloids
    Volume: 15
    Page numbers: 475-484
    Publisher: Elsevier Science(Oxford)
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