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PROF STEPHEN MARSDEN JANE



Contact Details

Organization: Medicine - Royal Melbourne and Western Hospitals
Position: NHMRC RESEARCH FELLOW
Email:

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science Institution not known
Bachelor of Medicine Institution not known
Doctor of Philosophy Institution not known

Fellowships

Fellowship Date Awarded
Fellow of the Royal Australasian College of Physicians (FRACP)
Fellow of the Royal College of Pathologists, Australia (FRCPA)

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
STUDIES OF NF-E4, A NOVEL FETAL/ERYTHROID SPECIFIC FACTOR INVOLVE FETAL GLOBIN GENE REGULATION Chief Investigator NHMRC Research Fellowship 01/01/2001
Identification and characterisation of novel factors that regulate fetal glbin gene expression Principal Supervisor NHMRC Medical & Dental Postgraduate Scholarships 01/01/2003
NHMRC Research Fellowship Chief Investigator NHMRC Research Fellowship 01/01/2005
ANALYSIS OF THE INTERACTION OF THE T-CELL ONCOPROTEINS SCL AND LMO2 IN T CELL ACUTE LYMPHOBLASTIC LEUKAEMIA Chief Investigator NHMRC Project Grants 01/01/2008
CHARACTERISATION OF ERYTHROPOIETIC MUTANTS IDENTIFIED IN A FORWARD GENETIC SCREEN IN MICE Chief Investigator NHMRC Project Grants 01/01/2008
DEFECTS IN EPIDERMAL MORPHOGENESIS IN MAMMALIAN GRAINYHEAD-LIKE GENE DEFICIENT MICE Chief Investigator NHMRC Project Grants 01/01/2008
THE ROLE OF THE MAMMALIAN GRAINYHEAD-LIKE GENE FAMILY IN NEURAL TUBE CLOSURE Chief Investigator NHMRC Project Grants 01/01/2008
IDENTIFICATION OF NOVEL MECHANISMS GOVERNING STAGE-SPECIFIC REGULATION OF THE HUMAN GLOBIN GENES Chief Investigator NHMRC Project Grants 01/01/2008
ANALYSIS OF FACTORS GOVERNING GLOBIN GENE EXPRESSION Chief Investigator NHMRC Project Grants 01/01/2008

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • Grhl3 and Lmo4 play coordinate roles in epidermal migration
    Year: 2008
    Journal: Developmental Biology
    Volume: 321
    Issue: 1
    Page numbers: 263-272
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  • Perturbed desmosomal cadherin expression in grainy head-like 1-null mice
    Year: 2008
    Journal: EMBO Journal
    Volume: 27
    Page numbers: 886-897
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Publications in 2007

Journal Articles

  • Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene
    Year: 2007
    Journal: Blood
    Volume: 110
    Issue: 10
    Page numbers: 3573-3581
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  • The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge.
    Year: 2007
    Journal: Oncogene
    Volume: 26
    Issue: 16
    Page numbers: 2272-82
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Publications in 2006

Journal Articles

  • A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis.
    Year: 2006
    Journal: Blood
    Volume: 108
    Issue: 7
    Page numbers: 2248-2256
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  • Functional interaction of CP2 with GATA-1 in the regulation of erythroid promoters.
    Year: 2006
    Journal: Molecular and Cellular Biology
    Volume: 26
    Issue: 10
    Page numbers: 3942-3954
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  • Repression of human gamma-globin gene expression by a short isoform of the NF-E4 protein is associated with loss of NF-E2 and RNA polymerase II recruitment to the promoter.
    Year: 2006
    Journal: Blood
    Volume: 107
    Issue: 5
    Page numbers: 2138-2145
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  • Spatial and temporal expression of the Grainyhead-like transcription factor family during murine development.
    Year: 2006
    Journal: Gene Expression Patterns
    Volume: 6
    Page numbers: 964-970
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Publications in 2005

Journal Articles

  • A homolog of Drosophila grainy head is essential for epdermal integrity in mice
    Year: 2005
    Journal: Science
    Volume: 308
    Page numbers: 411-413
    Publisher: American Society for the Advancement of Science(Washington DC)
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  • Adoptive transfer of gene-engineered CD4+ helper T cells induces potent primary and secondary tumor rejection
    Year: 2005
    Journal: Blood
    Volume: 106
    Page numbers: 2995-3003
    Publisher: American Society of Hematology(Washington DC)
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  • Epidermal impermeable barriers in mouse and fly
    Year: 2005
    Journal: Current Opinion in Genetics and Development
    Volume: 15
    Page numbers: 447-453
    Publisher: Current Biology(London)
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  • Functional but abnormal adult erthropoiesis in the absence of the stem cell leukemia gene
    Year: 2005
    Journal: Molecular and Cellular Biology
    Volume: 25
    Page numbers: 6355-6362
    Publisher: American Society for Microbiology(Washington DC)
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  • MBP4-dependent expression of Xenopus grainyhead-like 1 is essential for epidermal differentiation
    Year: 2005
    Journal: Development
    Volume: 132
    Page numbers: 1021-1034
    Publisher: Company of Biologists(Cambridge)
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  • T cells gene-engineered with DAP12 mediate effector function in an NKG2D-dependent and major histocompatibility complex-independent manner
    Year: 2005
    Journal: Journal of Biological Chemistry
    Volume: 280
    Page numbers: 38235-38241
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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Publications in 2004

Journal Articles

  • A functional role for CD28 costimulation in tumor recognition by single-chain receptor-modified T cells
    Year: 2004
    Journal: Cancer Gene Therapy
    Volume: 11
    Page numbers: 371-379
    Publisher: Nature Publishing Group(London)
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  • Defective extraembryonic angiogenesis in mice lacking LBP-1a, a member of the grainyhead family of transcription factors
    Year: 2004
    Journal: Molecular and Cellular Biology
    Volume: 24
    Page numbers: 7113-7129
    Publisher: American Society for Microbiology(Washington DC)
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  • Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium
    Year: 2004
    Journal: Blood
    Volume: 104
    Page numbers: 1769-1777
    Publisher: American Society of Hematology(Washington DC)
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  • Mutational analysis of P-glycoprotein: suppression of caspase activation in the absence of ATP-dependent drug efflux
    Year: 2004
    Journal: Cell Death & Differentiation
    Volume: 11
    Page numbers: 1028-1037
    Publisher: Nature Publishing Group(Basingstroke)
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  • SCL is required for normal function of short-term repopulating hematopoietic stem cells
    Year: 2004
    Journal: Blood
    Volume: 103
    Page numbers: 3342-3348
    Publisher: American Society of Hematology(Washington DC)
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  • Site-specific acetylation of the fetal globin activator NF-E4 prevents its ubiquitination and regulates its interaction with the histone deacetylase, HDAC1
    Year: 2004
    Journal: Journal of Biological Chemistry
    Volume: 279
    Page numbers: 41477-41486
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • The functional basis for hemophagocytic lymphohistiocytosis in a patient with co-inherited Missense mutations in the perforin (PFN1) gene
    Year: 2004
    Journal: Journal of Experimental Medicine
    Volume: 200
    Page numbers: 811-816
    Publisher: Rockefeller University Press(New York)
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  • The role of p22 NF-E4 in human globin gene switching
    Year: 2004
    Journal: Journal of Biological Chemistry
    Volume: 279
    Page numbers: 26227-26232
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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Publications in 2003

Journal Articles

  • Identification and characterization of mechanistically distinct inducers of gammaglobulin transcription
    Year: 2003
    Journal: Biochemical Pharmacology
    Volume: 66
    Page numbers: 1755-1768
    Publisher: Pergamon-Elsevier Science(Oxford)
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  • Inositol- and folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3
    Year: 2003
    Journal: Nature Medicine
    Volume: 9
    Page numbers: 1513-
    Publisher: Nature America(New York)
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  • The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12
    Year: 2003
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 100
    Page numbers: 992-997
    Publisher: National Academy of Sciences(Washington DC)
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  • The identification and characterization of human sister-of-mammalian grainyhead (SOM) expands the grainyhead-like family of developmental transcription factors
    Year: 2003
    Journal: Biochemical Journal
    Volume: 370
    Page numbers: 953-962
    Publisher: Portland Press(London)
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Publications in 2002

Journal Articles

  • A highly conserved novel family of mammalian developmental transcription factors related to Drosophila grainyhead
    Year: 2002
    Journal: Mechanisms of Development
    Volume: 114
    Page numbers: 37-50
    Publisher: Elsevier Science(Amsterdam)
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  • Binding of the RING polycomb proteins to specific target genes in complex with the grainyhead-like family of developmental transcription factors
    Year: 2002
    Journal: Molecular and Cellular Biology
    Volume: 22
    Page numbers: 1936-1946
    Publisher: American Soci