Selected publications
2012
Journal Articles Refereed
- Impact of 18 F-FDG-PET in decision making for liver metastectomy of colorectal cancer. ANZ Journal of Surgery. 82:30-35. 2012
- Intensity modulated radiation therapy dose painting for localized prostate cancer using C-choline positron emission tomography scans. International Journal of Radiation: Oncology - Biology - Physics. 83:e691-e696. 2012
- Macromolecule Functionalization of Disulfide-Bonded Polymer Hydrogel Capsules and Cancer Cell Targeting. ACS Nano. 6:1463-1472. 2012
- Oncology health information quality on the internet: a multilingual evaluation. Annals of Surgical Oncology. 19:706-713. 2012
- PET in prostate and bladder tumors. Seminars in Nuclear Medicine. 42:231-246. 2012
- Prognostic Ability of F-18-FDG PET/CT in the Assessment of Colorectal Liver Metastases.. Journal of Nuclear Medicine. 53:1345-1351. 2012
2011
Research Book Chapters
- The Delivery Construct: Maximising the Therapeutic Ratio of Targeted Radionuclide Therapy, in Targeted Radionuclide Therapy. Targeted Radkonuclide Therapy. Lippincott Williams & Wilkins. 236-248. 2011
Journal Articles Refereed
- A simplified protocol for the automated production of succinimidyl 4-18 F fluorobenzoate on an IBA Synthera module. Journal of Labelled Compounds & Radiopharmaceuticals. 54:671-673. 2011
- Compliance with PET acquisition protocols for therapeutic monitoring of erlotinib therapy in an international trial for patients with non-small cell lung cancer. European Journal of Nuclear Medicine and Molecular Imaging. 38:642-650. 2011
- Establishing locoregional control of malignant pleural mesothelioma using high-dose radiotherapy and F-18-FDG PET/CT scan correlation. Journal of Medical Imaging and Radiation Oncology. 55:320-332. 2011
- Histopathological correlation of C-11-choline PET scans for target volume definition in radical prostate radiotherapy. Radiotherapy and Oncology. 99:187-192. 2011
- Investigation of hypoxia and carbonic anhydrase IX expression in a renal cell carcinoma xenograft model with oxygen tension measurements and I-124-cG250 PET/CT. Urologic Oncology - Seminars and Original Investigations. 29:411-420. 2011
- Long-term survival of 42 patients with resected N2 non-small-cell lung cancer: the impact of 2-18 F-fluoro-2-deoxy-D -glucose positron emission tomogram mediastinal staging. European Journal of Cardio-Thoracic Surgery. 39:96-101. 2011
- Structural Basis for Fc gamma RIIa Recognition of Human IgG and Formation of Inflammatory Signaling Complexes. Journal of Immunology. 187:3208-3217. 2011
- Synthesis of a F-18fluoroethyltriazolylthymidine radiotracer from F-182-fluoroethyl azide and 5-ethynyl-2 '-deoxyuridine. Journal of Labelled Compounds & Radiopharmaceuticals. 54:260-266. 2011
2010
Journal Articles Refereed
- Dopamine D-1 receptor binding in the anterior cingulate cortex of patients with obsessive-compulsive disorder. Psychiatry Research - Neuroimaging. 183:85-88. 2010
- Efficiency of T-cell costimulation by CD80 and CD86 cross-linking correlates with calcium entry. Immunology. 129:28-40. 2010
- Global trends in hybrid imaging. Radiology. 257:498-506. 2010
- MAb 806 enhances the efficacy of ionizing radiation in glioma xenografts expressing the de2-7 epidermal growth factor receptor. International Journal of Radiation: Oncology - Biology - Physics. 78:572-578. 2010
- Targeting of Cancer Cells Using Click-Functionalized Polymer Capsules. Journal of the American Chemical Society. 132:15881-15883. 2010
Journal Articles Unrefereed Letters or Notes
- Functional imaging of renal cell carcinoma. Nature Reviews Urology. 7:258-266. 2010
- Potential of imaging biomarkers for characterization of renal masses. Expert Review of Anticancer Therapy. 10:781-786. 2010
Other Refereed Contribution to Refereed Journals
- Benign ectopic multinodular thyroid tissue in the submandibular region with a coexistent normotopic multinodular thyroid gland harboring papillary thyroid cancer. Clinical Nuclear Medicine. 35:618-619. 2010
2009
Book Chapters Other
- Prostate Carcinoma: Radionuclide Imaging and PET. Imaging in Oncological Urology. Springer-Verlag London. 249-268. 2009
Journal Articles Refereed
- A possible role for metallic ions in the carbohydrate cluster recognition displayed by a Lewis Y specific antibody. PLoS One. 4:0-0. 2009
- A truncated soluble epidermal growth factor receptor-Fc fusion ligand trap displays anti-tumour activity in vivo. Growth Factors. 27:141-154. 2009
- Antibodies specifically targeting a locally misfolded region of tumour associated EGFR. Proceedings of the National Academy of Sciences of the United States of America. 106:5082-5087. 2009
- Dopamine D1 receptor binding in the striatum of patients with obsessive-compulsive disorder. Journal of Affective Disorders. 114:321-326. 2009
- Established, emerging and future roles of PET/CT in the management of colorectal cancer. Clinical Radiology. 64:225-237. 2009
- Imaging of deep venous thrombosis in patients using a radiolabelled anti-D-dimer Fab' fragment (99m Tc-DI-DD3B6/22-80B3): results of a phase I trial. European Journal of Nuclear Medicine and Molecular Imaging. 36:250-259. 2009
- Phase I biodistribution and pharmacokinetic study of Lewis Y-targeting immunoconjugate CMD-193 in patients with advanced epithelial cancers. Clinical Cancer Research. 15:6709-6715. 2009
- Positron emission tomography changes management and prognostic stratification in patients with oesophageal cancer: results of a multicentre prospective study. European Journal of Nuclear Medicine and Molecular Imaging. 36:354-361. 2009
- Positron emission tomography changes management, improves prognostic stratification and is superior to gallium scintigraphy in patients with low-grade lymphoma: results of a multicentre prospective study. European Journal of Nuclear Medicine and Molecular Imaging. 36:347-353. 2009
- Prognostic value of 18 F-FDG PET/CT in patients with malignant pleural mesothelioma. Molecular Imaging and Biology. 11:473-479. 2009
- Targeted therapy of renal cell carcinoma: Synergistic activity of cG250-TNF and IFNg. International Journal of Cancer. 125:115-123. 2009
- Targeting a unique EGFR epitope with monoclonal antibody 806 activates NF-κB and initiates tumor vascular normalization. Journal of Cellular and Molecular Medicine. 13:3993-4001. 2009
- The Lewis-Y carbohydrate antigen is expressed by many human tumors and can serve as a target for genetically redirected T cells despite the presence of soluble antigen in serum. Journal of Immunotherapy. 32:292-301. 2009
- The plasticity of oncogene addiction: implications for targeted therapies directed to receptor tyrosine kinases. NeoPlasia. 11:448-458. 2009
- Therapeutic efficacy of 177 Lu-CHX-A"-DTPA-hu3S193 radioimmunotherapy in prostate cancer is enhanced by EGFR inhibition or docetaxel chemotherapy. The Prostate. 69:92-104. 2009
Journal Articles Unrefereed Letters or Notes
- Medullary carcinoma of the thyroid in a patient with colon cancer and a rising carcinoembryonic antigen level. Internal Medicine Journal. 39:264-265. 2009
2008
Research Book Chapters
- Clinical Radionuclide Tumor Therapy. Targeted radionuclide tumor therapy: Biological aspecsts. Springer London. 349-385. 2008
Journal Articles Refereed
- Assessing the impact of FDG-PET in the management of anal cancer. Radiotherapy and Oncology. 87:376-382. 2008
- Humoral immune responses in patients vaccinated with 1-146 HER2 protein complexed with cholesteryl pullulan nanogel. Cancer Science. 99:601-607. 2008
- PET changes management and improves prognostic stratification in patients with head and neck cancer: results of a multicenter prospective study. Journal of Nuclear Medicine. 49:1593-1600. 2008
- PET changes management and improves prognostic stratification in patients with recurrent coclorectal cancer: results of a multicenter prospective study. Journal of Nuclear Medicine. 49:1451-1457. 2008
- Role of low-dose, noncontrast computed tomography from integrated positron emission tomography/computed tomography in evaluating incidental 2-deoxy-2-F-18fluoro-D-glucose-avid colon lesions. Molecular Imaging and Biology. 10:48-53. 2008
- Tumor targeting by a multivalent single-chain Fv (scFv) anti-Lewis Y antibody construct. Cancer Biotherapy & Radiopharmaceuticals. 23:411-423. 2008
2007
Journal Articles Refereed
- A Phase I Biodistribution and Pharmacokinetic Trial of Humanized Monoclonal Antibody Hu3s193 in Patients with Advanced Epithelial Cancers that Express the Lewis-Y Antigen. Clinical Cancer Research. 13:3286-3292. 2007
- A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors. Proceedings of the National Academy of Sciences of the United States of America. 104:4071-4076. 2007
- A pilot study of monoclonal antibody cG250 and low dose subcutaneous IL-2 in patients with advanced renal cell carcinoma. Cancer Immunity. 7:14-14. 2007
- Anterior cingulate activation in antipsychotic-naive first episode schizophrenia. Acta Psychiatrica Scandinavica. 115:155-158. 2007
- Diagnostic and therapeutic use of radioisotopes for bony disease in prostate cancer: Current practice. International Journal of Urology. 14:89-95. 2007
- Hypoxia positron emission tomography imaging with (18)f-fluoromisonidazole. Seminars in Nuclear Medicine. 37:451-461. 2007
- Influence of size, surface, cell line and kinetic properties on the specific binding of A33 anitgen-targeted multilayered paricles and capsules to colorectal cancer cells.. ACS Nano. 1:93-102. 2007
- Prevalence of occult metastatic disease in patients undergoing 18F-FDG PET for primary diagnosis or staging of lung carcinoma and solitary pulmonary nodules. Internal Medicine Journal. 37:753-759(7). 2007
- Radioimmunotherapy with -Particle–Emitting 213Bi-C-Functionalized trans-Cyclohexyl-Diethylenetriaminepentaacetic Acid-Humanized 3S193 Is Enhanced by Combination with Paclitaxel Chemotherapy. Clinical Cancer Research. 13:5604S-5612S. 2007
- The Efficacy of Epidermal Growth Factor Receptor–Specific Antibodies against Glioma Xenografts Is Influenced by Receptor Levels, Activation Status, and Heterodimerization. Clinical Cancer Research. 13:1911-1925. 2007
- The Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor AG1478 Increases the Formation of Inactive Untethered EGFR Dimers. Journal of Biological Chemistry. 282:2840-2850. 2007
- Therapeutic anti-EGFR antibody 806 generates responses in murine de novo EGFR mutant–dependent lung carcinomas. Journal of Clinical Investigation. 117:346-352. 2007
Other Refereed Contribution to Refereed Journals
- Renal Cell Cancer and Positron Emission Tomography- an Evolving Diagnostic and Therapeutic Relationship. Current Medical Imaging Reviews. 3:17-26. 2007
- The expanding role of PET technology in the management of patients with colorectal cancer. Annals of Oncology. 18:1774-1781. 2007
2006
Research Book Chapters
- Molecular Imaging. Clinical Nuclear Medicine. Hodder Headline. 5-27. 2006
Journal Articles Refereed
- A phase I radioimmunolocalization trial of humanized monoclonal antibody huA33 in patients with gastric carcinoma. Cancer Science. 97:1248-1254. 2006
- Correlation of Hypoxic Cell Fraction and Angiogenesis with Glucose Metabolic Rate in Gliomas Using 18 F-Fluoromisonidazole, 18 F-FDG PET, and Immunohistochemical Studies. Journal of Nuclear Medicine. 47:410-418. 2006
- Enhanced Efficacy of 90Y-Radiolabeled Anti-Lewis Y Humanized Monoclonal Antibody hu3S193 and Paclitaxel Combined-Modality Radioimmunotherapy in a Breast Cancer Model. Nuclear Medicine and Biology. 47:716-725. 2006
- Evaluating brain activity in obsessive-compulsive disorder: Preliminary insights from a multivariate analysis. Psychiatry Research. 147:227-231. 2006
- F-18 labelled N,N-bis -haloethylamino-phenylsulfoxides - a new class of compounds for the imaging of hypoxic tissue. Journal of Labelled Compounds & Radiopharmaceuticals. 49:1089-1103. 2006
- Fluorine-18 fluorothymidine: A new positron emission radioisotope for renal tumors. Clinical Nuclear Medicine. 31:788-789. 2006
- Novel Imaging Techniques in Melanoma. Surgical Oncology Clinics of North America. 15:253-283. 2006
- Positron emission tomography (PET), immuno-PET and radioimmunotherapy in renal cell carcinoma: a developing diagnostic and therapeutic relationship.. BJU International. 97:916-922. 2006
- Positron emission tomography and molecular imaging of the prostate: an update. BJU International. 97:923-931. 2006
- Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine Kinase. Biochemical Pharmacology. 71:1422-1434. 2006
- Relationship of Hepatic Functional Imaging to Irinotecan Pharmacokinetics and Genetic Parameters of Drug Elimination. Clinical Oncology. 24:4228-4235. 2006
- Role of Nuclear Medicine in the Management of Cutaneous Malignant Melanoma. Journal of Nuclear Medicine. 47:957-967. 2006
- Xenografting Tumour beneath the Renal Capsule Using Modern Surgical Equipment. European Surgical Research. 38:340-346. 2006
2005
Research Book Chapters
- PET imaging in Oncology. Positron Emission Tomography. Springer Verlag. 311-325. 2005
Journal Articles Refereed
- A phase 1 trial of humanized monoclonal antibody A33 in patients with colorectal carcinoma: biodistribution, pharmacokinetics, and quantitative tumor uptake. Clinical Cancer Research. 11:4810-4817. 2005
- Assessing regional hypoxia in human renal tumours using 18F-Fluoromisonidazole 18F-FMISO positron emission tomography.. BJU International. 96:540-546. 2005
- Assessment of the role of FDG PET in the diagnosis and management of children with refractory epilepsy. European Journal of Nuclear Medicine and Molecular Imaging. 32:1311-1316. 2005
- Concurrent binding of anti-ephA3 antibody and ephrin-A5 amplifies ephA3 signaling and downstream responses: potential as ephA3-specific tumor-targeting reagents. Cancer Research. 65:6745-6754. 2005
- Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFR. British Journal of Cancer. 92:1069-1077. 2005
- Enhanced Efficacy of Radioimmunotherapy with 90 Y-CHX-A-DTPA-hu3S193 by Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling with EGFR Tyrosine Kinase Inhibitor AG1478. Clinical Cancer Research. 11:7080S-7086S. 2005
- Impact of 2-Deoxy-2F-18Fluoro-D-Glucose positron emission tomography on the management of patients with advanced melanoma. Molecular Imaging and Biology. 7:304-308. 2005
- Phase I Trial of 131I-huA33 in Patients with Advanced Colorectal Carcinoma. Clinical Cancer Research. 11:4818-4826. 2005
- Positron emission tomography with selected mediastinoscopy compared to routine mediastinoscopy offers cost and clinical outcome benefits for pre-operative staging of non-small cell lung cancer. European Journal of Nuclear Medicine and Molecular Imaging. 32:1033-1040. 2005
- Radiation dose to PET technologists and strategies to lower occupational exposure. Journal of Nuclear Medicine Technology. 33:44-47. 2005
- Recombinant NY-ESO-1 cancer antigen: Production and purification under cGMP conditions. Preparative Biochemistry & Biotechnology. 35:119-134. 2005
- Synthesis, 11 C labeling and biological properties of derivatives of the tyrphostin AG957. Nuclear Medicine and Biology. 32:323-328. 2005
- The antitumor monoclonal antibody 806 recognizes a high-mannose form of the EGF receptor that reaches the cell surface when cells over-express the receptor. FASEB Journal. 19:780-782. 2005
- Treatment of Human Tumour Xenografts with Monoclonal Antibody 806 in Combination with a Prototypical Epidermal Growth Factor Receptor - Specific Antibody Generates Enhanced Antitumour Activity.. Clinical Cancer Research. 11:6390-6399. 2005
- Utility of FMISO PET in advanced head and neck cancer treated with chemoradiation incorporating a hypoxia-targeting chemotherapy agent. European Journal of Nuclear Medicine and Molecular Imaging. 32:1-14. 2005
Journal Articles Unrefereed
- Immunological effects of chimeric anti-GD3 monoclonal antibody KM871 in patients with metastatic melanoma. Cancer Immunity. 5. 2005
- Radioimmunotherapy of prostate cancer: does tumor size matter?. Journal of Clinical Oncology. 23:4567-4569. 2005
2004
Journal Articles Refereed
- 18 F-Fluorodeoxyglucose positron emission tomography in evaluation of germ cell tumor after chemotherapy. Urology. 64:1202-1207. 2004
- BF3 etherate catalysed formation of 11 Cmethyl esters: a novel radiolabelling technique. Journal of Labelled Compounds & Radiopharmaceuticals. 47:523-530. 2004
- CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor. Journal of Biological Chemistry. 279:22387-22398. 2004
- Detection of occult bone metastases of lung cancer with Fluorine-18 fluorodeoxyglucose positron emission tomography. Australasian Radiology. 48:214-216. 2004
- Functional imaging of intratumoral hypoxia. Molecular Imaging and Biology. 6:291-305. 2004
- Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor. Journal of Biological Chemistry. 279:30375-30384. 2004
- Population pharmacokinetics of sibrotuzumab, a novel therapeutic monoclonal antibody, in cancer patients. Investigational New Drugs. 22:39-52. 2004
- Positron emission tomography scanning in the assessment of patients with lymphoma. Internal Medicine Journal. 34:388-397. 2004
- Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans. Proceedings of the National Academy of Sciences of the United States of America. 101:10697-10702. 2004
- Structural convergence of antibody binding of carbohydrate determinants in Lewis Y tumor antigens. Journal of Molecular Biology. 340:809-818. 2004
- Synthesis and evaluation of a thymidine analog for positron emission tomography study of tumor DNA proliferation in vivo. Nuclear Medicine and Biology. 31:839-849. 2004
- Targeted biocactivity of membrane-anchored TNF by an antibody-derived TNF fusion protein. Journal of Immunology. 172:3930-3939. 2004
- The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR. Oncogene. 23:6095-6104. 2004
2003
Journal Articles Unrefereed
- A novel method for determining hepatic sinusoidal oxygen permeability in the isolated perfused rat liver using 15OO2. Nuclear Medicine and Biology. 30:93-100. 2003
2001
Journal Articles Refereed
- Biodistribution properties of (111)Indium-labeled C-functionalized trans-cyclohexyl diethylenetriaminepentaacetic acid humanized 3S193 diabody and F(ab ')(2) constructs in a breast carcinoma xenograft model. Clinical Cancer Research. 7:1061-1072. 2001
- Clinical role of F-18 fluorodeoxyglucose positron emission tomography for detection and management of renal cell carcinoma. Journal of Urology. 166:825-830. 2001
- Construction, expression and characterisation of a single-chain diabody derived from a humanised anti-Lewis Y cancer targeting antibody using a heat-inducible bacterial secretion vector. Cancer Immunology, Immunotherapy. 50:241-250. 2001
- Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb)806, a novel monoclonal antibody directed to the receptor. Cancer Research. 61:5349-5354. 2001
- Immuno-pet of human colon xenograft- bearing balb/c nude mice using (124)i-cdr-grafted humanized a33 monoclonal antibody. Journal of Nuclear Medicine. 42:764-769. 2001
- Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR. Cancer Research. 61:5355-5361. 2001
- Overexpression of insulin-like growth factor binding protein-6 inhibits rhabdomyosarcoma growth in vivo. International Journal of Cancer. 94:645-651. 2001
- Population pharmacokinetics of antifibroblast activation protein monoclonal antibody F19 in cancer patients. British Journal of Clinical Pharmacology. 51:177-180. 2001
- Relative therapeutic efficacy of 125I- and 131I- labeled monoclonal antibody A33 in a human colon cancer xenograft. Journal of Nuclear Medicine. 42:1251-1256. 2001
- Specific localization, gamma camera imaging, and intracellular trafficking of radiolabelled chimeric anti-GD3 ganglioside monoclonal antibody KM871 in SK-MEL-28 melanoma xenografts. Cancer Research. 61:4474-4482. 2001
- Targeting properties of an anti-CD16/anti-CD30 biospecific antibody in an in vivo system. Cancer Immunology, Immunotherapy. 50:102-108. 2001
