Electron microscopy and tomography (cardiac cell, ultrastructure)
Microfluidics cell culturing and imaging (cancer cell motility)
soft tissue mechanics (breast cancer image analysis)
Dr Vijay Rajagopal is a Senior Lecturer at the Department of Mechanical Engineering at the University of Melbourne. Vijay moved to the University of Melbourne at the start of 2014 to establish a new research program in ‘cell structure and mechanics’ to measure the 3D spatial organization of cells and their local environment to address questions about structure/function relationships from the sub-cellular to inter-cellular scale of human physiology.
Vijay started his research career as a PhD student at the Auckland Bioengineering Institute, University of Auckland, NZ. His interests were in developing software to track breast tumours across clinical MR, ultrasound and x-ray images. His research involved the development of robust computational models of the breast of individual patients that would predict the movement of tumours identified in one imaging modality across to the other modalities used in clinical practice. His research received international recognition as the runner-up in the MICCAI Young Scientist of the Year in 2007 – the top peer-reviewed conference for medical image computing and computer aided image analysis. His work also received national recognition as he was also the finalist of the NZ Young Scientist of the Year in recognition of the clinically relevant and methodological approach of his research.
Since completing his PhD in 2007, Vijay shifted his interests to a new found curiosity in understanding how the organization of subcellular components of cells and their placement in their 3D environment affects their overall behaviour. He began a new research group within the Auckland Bioengineering Institute to look at the 3D organization of the cardiac cell ultrastructure and developed skills in electron tomography and confocal microscopy through new collaborations he established between the University of Exeter and the University of California San Diego. He subsequently moved to a Research Scientist
Students with interests in computational modeling, image processing and or imaging and experimental methods such as electron tomography, confocal microscopy and microfludics-based cell culturing methods are welcome to get in touch with me regarding possible projects. Key areas of research: Cell structure remodelling in diabetic cardiomyopathy; cardiac hypertrophy; cancer cell motility