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PROF FRANCES SEPAROVIC

Positions

Academic, Chemistry

NMR and membrane structure (biomolecular structure, antibiotic peptides, amyloid, solid-state NMR, toxins, biological membranes)
Membrane biophysics (biological solid-state NMR, lipid-peptide interactions)

Overview

OverviewText1

European Biophysics Journal, Editor (2012); Accounts in Chemical Research, Editorial Advisory Board (2009-); Honorary Research Fellow, School of Crystallography, Birkbeck College, University of London, UK (2008-2009); Biochimica Biophysica Acta: Biomembranes, Editor (2006-); Adjunct Professor of Chemistry & Biochemistry, College of Sciences, San Diego State University, USA (2001-2011); Associate Senior Member, St Hugh's College, University of Oxford, UK (2000-2007); Concepts in Magnetic Resonance, Editorial Board (1996-2009); University of Melbourne (1996-); National Institutes of Health, Bethesda, USA (1994-1995); CSIRO Food Research (1972-1995)

Has subject area

For 2008 6 Digit Code
- Characterisation of Biological Macromolecules
- Human Biophysics
Seo 2008 6 Digit Code
- Expanding Knowledge in the Chemical Sciences
- Expanding Knowledge in the Physical Sciences

Affiliation

Member of

American Chemical Society. Member 2009 -
International Conference on Magnetic Resonance in Biological Systems. ICMRBS 2010 Treasurer 2008 -
Royal Australian Chemical Institute. Honorary General Treasurer (2008-2010) 1996 -
Australian & New Zealand Society for Magnetic Resonance. President (2011-13) 1995 -
International Society for Magnetic Resonance. Chair, Nominating Committee (2009-) 1995 -
Biophysical Society (USA). National Program Committee (2008-2011) 1986 -
Australian Society for Biophysics. Public Officer, President Elect (2011-2012) 1979 -
Biophysical Society (USA). Council (2007-2010), International Committee (2008-), Nominating Committee (2010-) 2007 - 2010
International Union of Pure & Applied Biophysics. Member 2002 - 2005

Publications

Selected publications

2013
- Journal Articles Refereed
  - A practical implementation of de-Pake-ing via weighted Fourier transformation. PeerJ. 1:1-8. 2013
  - Structural effects of the antimicrobial peptide maculatin 1.1 on supported lipid bilayers. European Biophysics Journal with Biophysics Letters. 42:47-59. 2013
  - The importance of tryptophan B28 in H2 relaxin for RXFP2 binding and activation. International Journal of Peptide Research and Therapeutics. 19:55-60. 2013
2012
- Journal Articles Refereed
  - Copper Modulation of Amyloid Beta 42 Interactions with Model Membranes. Australian Journal of Chemistry. 65:472-479. 2012
  - Electrochemistry of room temperature protic ionic liquids: a critical assessment for use as electrolytes in electrochemical applications. Journal of Physical Chemistry B. 116:9160-9170. 2012
  - Host-defense peptides of Australian anurans. Part 2. Structure, mechanism of action, and evolutionary significance.. Peptides. 37:174-188. 2012
  - Human relaxin-2: historical perspectives and role in cancer biology. Amino Acids. 43:1131-1140. 2012
  - Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of H2 relaxin. Journal of Biological Chemistry. 287:41152-41164. 2012
  - Lipid composition regulates the conformation and insertion of the antimicrobial peptide maculatin 1.1. Biochimica et Biophysica Acta-Biomembranes. 1818:205-211. 2012
  - Minimization of Human Relaxin-3 Leading to High-Affinity Analogues with Increased Selectivity for Relaxin-Family Peptide 3 Receptor (RXFP3) over RXFP1. Journal of Medicinal Chemistry. 55:1671-1681. 2012
  - Surface immobilization of bio-functionalized cubosomes: sensing of proteins by quartz crystal microbalance. Langmuir. 28:620-627. 2012
  - The antimicrobial peptide aurein 1.2 disrupts model membranes via the carpet mechanism. Physical Chemistry Chemical Physics. 14:15739-15751. 2012
  - The lipid network. Biophysical Reviews. 4:283-290. 2012
- Journal Articles Unrefereed Letters or Notes
  - Membrane protein structure and function. Biochimica et Biophysica Acta-Biomembranes. 1818. 2012
2011
- Research Book Chapters
  - Solid-State NMR of Membrane-Acting Antimicrobial Peptides. Biomolecular NMR Spectroscopy. IOS Press. 137-161. 2011
  - Solid-state NMR of amyloid membrane interactions. Protein Folding, Misfolding, and Disease. Humana Press. 165-177. 2011
- Journal Articles Refereed
  - Design and Development of Analogues of Dimers of Insulin-like Peptide 3 B-Chain as High-Affinity Antagonists of the RXFP2 Receptor. Biopolymers. 96:81-87. 2011
  - Development of Cubosomes as a Cell-Free Biosensing Platform. Australian Journal of Chemistry. 64:46-53. 2011
  - Disentanglement of heterogeneous dynamics in mixed lipid systems. Biophysical Journal. 100:L40-L42. 2011
  - General method for selective labelling of double-chain cysteine-rich peptides with a lanthanide chelate via solid-phase synthesis. Journal of Peptide Science. 17:169-173. 2011
  - Interactions of a synthetic Leu–Lys-rich antimicrobial peptide with phospholipid bilayers. European Biophysics Journal with Biophysics Letters. 40:471-480. 2011
  - Interactions of the antimicrobial peptide maculatin 1.1 and analogues with phospholipid bilayers. Australian Journal of Chemistry. 64:798-805. 2011
  - Lipid matrix plays a role in Abeta fibril kinetics and morphology. FEBS Letters. 585:749-754. 2011
  - Modeling the membrane environment for membrane proteins. Biophysical Journal. 100:2073-2074. 2011
  - Preparation and biological evaluation of self-assembled cubic phases for the polyvalent inhibition of cholera toxin. Soft Matter. 7:6125-6134. 2011
  - QCM-D fingerprinting of membrane-active peptides. European Biophysics Journal with Biophysics Letters. 40:437-446. 2011
  - Stereospecific interactions are necessary for Alzheimer disease amyloid-beta toxicity. Neurobiology of Aging. 32:235-248. 2011
  - The relaxin peptide family--structure, function and clinical applications.. Protein and Peptide Letters. 18:220-229. 2011
- Journal Articles Unrefereed Letters or Notes
  - Special issue on membrane-active peptides. European Biophysics Journal with Biophysics Letters. 40:347-348. 2011
2010
- Journal Articles Refereed
  - Anionic Phospholipid Interactions of the Prion Protein N Terminus Are Minimally Perturbing and Not Driven Solely by the Octapeptide Repeat Domain. Journal of Biological Chemistry. 285:32282-32292. 2010
  - Effect of helix-promoting strategies on the biological activity of novel analogues of the B-chain of INSL3. Amino Acids. 38:121-131. 2010
  - NMR Relaxation and Self-Diffusion Study at High and Low Magnetic Fields of Ionic Association in Protic Ionic Liquids. Journal of Physical Chemistry B. 114:11436-11443. 2010
  - Non-Newtonian viscous shear-thinning in ionic liquids. Soft Matter. 6:2080-2086. 2010
  - Preparation of protic ionic liquids with minimal water content and 15N NMR study of proton transfer. Physical Chemistry Chemical Physics. 12:1571-1577. 2010
  - Real-time quantitative analysis of lipid disordering by aurein 1.2 during membrane adsorption, destabilisation and lysis. Biochimica et Biophysica Acta-Biomembranes. 1798:1977-1986. 2010
  - Self-Assembly of Peptides into Spherical Nanoparticles for Delivery of Hydrophilic Moieties to the Cytosol. ACS Nano. 4:2856-2864. 2010
  - Solid-state NMR and simulation studies of equinatoxin II N-terminus interaction with lipid bilayers. Proteins - Structure, Function, and Bioinformatics. 78:858-872. 2010
  - Solid-state NMR study of membrane interactions of the pore-forming cytolysin, equinatoxin II. Biochimica et Biophysica Acta-Biomembranes. 1798:244-251. 2010
2009
- Research Book Chapters
  - Development of lanthanide-labelled human INSL3 as an alternative probe to radioactively-labelled INSL3 for use in bioassays. Relaxin and Related Peptides: Fifth International Conference, Ann NY Acad Sci Vol 1160. Wiley-Blackwell Publishing. 87-90. 2009
  - Host-Defense Peptides from the Secretion of the Skin Glands of Frogs and Toads: Membrane-Active Peptides from the Genera Litoria, Uperoleia, and Crinia. Bioactive Peptides. Taylor & Francis Ltd. 333-355. 2009
  - The Human Insulin Superfamily of Polypeptide Hormones . Vitamins and Hormones, Vol 80. Elsevier Science. 1-31. 2009
  - The chemistry and biology of insulin-like peptide 3, a novel member of the insulin superfamily.. Bioactive Peptides. Taylor & Francis Ltd. 159-168. 2009
- Journal Articles Refereed
  - Cubic phases of ternary amphiphile-water systems. European Biophysics Journal with Biophysics Letters. 39:83-90. 2009
  - Effect of lipid on the conformation of the N-terminal region of equinatoxin II: a synchrotron radiation circular dichroism spectroscopic study. European Biophysics Journal with Biophysics Letters. 39:121-127. 2009
  - Membrane Interactions of Antimicrobial Peptides from Australian Frogs. Biochimica et Biophysica Acta-Biomembranes. 1788:1630-1638. 2009
  - Physico-chemical characterization of structure and stability of rifampicin liposome dry powders for inhalation. Journal of Pharmaceutical Sciences. 98:628-639. 2009
  - The solution structure and membrane interactions of the antimicrobial peptide fallaxidin 4.2: an NMR and QCM study.. Biochemistry. 48:11892-11901. 2009
2008
- Journal Articles Refereed
  - A solid-state NMR study of the interaction of fish antifreeze proteins with phospholipid membranes. European Biophysics Journal with Biophysics Letters. 37:1031-1038. 2008
  - Effect of antimicrobial peptides from Australian tree frogs on anionic phospholipid membranes. Biochemistry. 47:8557-8565. 2008
  - Electrochemistry in room temperature protic ionic liquids.. Journal of Physical Chemistry B. 112:6923-6936. 2008
  - Liposomal phospholipid preparations of chloramphenicol for ophthalmic applications. Journal of Pharmaceutical Sciences. 97:2691-2701. 2008
  - Metal effects on the membrane interactions of amyloid-beta peptides. European Biophysics Journal with Biophysics Letters. 37:333-344. 2008
  - Metals and Membranes in Neuroscience. European Biophysics Journal with Biophysics Letters. 37:239-239. 2008
  - Solid-phase synthesis of europium-labeled human INSL3 as a novel probe for the study of ligand-receptor interactions. Bioconjugate Chemistry. 19:1456-1463. 2008
  - The effects of lipids on the structure of the eukaryotic cytolysin equinatoxin II: a synchrotron radiation circular dichroism spectroscopic study. Biochimica et Biophysica Acta-Biomembranes. 1778:2091-2096. 2008
- Conference Papers Refereed
  - Determination of rifampicin location in cholesterol-lipid liposomes by 2H and 31P solid-state NMR. 397-401. 2008
2007
- Research Book Chapters
  - Gated ion channel based biosensor device. Biological Membrane Ion Channels: Dynamics, Structure and Applications. Springer. 595-621. 2007
- Journal Articles Refereed
  - Beta-sheet structured beta-amyloid(1-40) perturbs phosphatidylcholine model membranes.. Journal of Molecular Biology. 368:982-987. 2007
  - Boltzmann statistics rotational-echo double resonance-analysis. Journal of Physical Chemistry B. 111:7802-7811. 2007
  - Characterization of extracellular polysaccharides produced by the fungus Acremonium. Carbohydrate Research. 342:2481-2483. 2007
  - Cholesterol and Clioquinol modulation of Ab(1-42) interaction with phospholipid bilayers and metals. Biochimica et Biophysica Acta-Biomembranes. 1768:3135-3144. 2007
  - Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase.. FEBS Journal. 274:1778-1785. 2007
  - Interactions of the Australian tree frog antimicrobial peptides aurein 1.2, citropin 1.1 and maculatin 1.1 with lipid model membranes: differential scanning calorimetric and Fourier transform infrared spectroscopic studies. Biochimica et Biophysica Acta-Biomembranes. 1768:2787-2800. 2007
  - International trend in biophysics - The Australian Society for Biophysics: a brief history.. Seibutsu Butsuri. 47:338-340. 2007
  - Membrane interactions and the effect of metal ions on the amyloidogenic fragment Ab(25-35) in comparison to Ab(1-42).. Biochimica et Biophysica Acta-Biomembranes. 1768:2400-2408. 2007
  - Selective permeabilization of the host cell membrane of Plasmodium falciparum-infected red blood cells by streptolysin O and equinatoxin II.. Biochemical Journal. 403:167-175. 2007
  - Solution structure and interaction of cupiennin 1a, a spider venom peptide, with phospholipid bilayers.. Biochemistry. 46:3576-3585. 2007
  - Specific and Selective Peptide-Membrane Interactions Revealed Using Quartz Crystal Microbalance. Biophysical Journal. 93:3907-3916. 2007
  - The conformation of acetylated virginiamycin M1 and virginiamycin M1 in explicit solvents.. Biochimica et Biophysica Acta-Biomembranes. 1774:610-618. 2007
- Journal Articles Unrefereed Letters or Notes
  - From physics to biology (book review). Australian Physics. 2007:30-30. 2007
- Conference Papers Unrefereed
  - 170 MQMAS NMR characterisation of geopolymers. 1272-1273. 2007
2006
- Research Book Chapters
  - Amino functionalisation of microemulsion templated mesoporous silica foams.. Studies in Surface Science and Catalysis (Characterisation of Porous Solids VII). Elsevier Science. 850-850. 2006
  - Solid-state NMR of membrane-active proteins and peptides. Modern Magnetic Resonance Part 1: Applications in Chemistry, Biological and Marine Sciences. Springer. 301-307. 2006
- Journal Articles Refereed
  - ³⁹ K NMR of free potassium in geopolymers. Industrial & Engineering Chemistry Research. 45:9208-9210. 2006
  - Amyloid-beta peptide disruption of lipid membranes and the effect of metal ions.. Journal of Molecular Biology. 356:759-770. 2006
  - Copper and Zinc Mediated Oligomerisation of Abeta peptides. International Journal of Peptide Research and Therapeutics. 12:153-164. 2006
  - Copper-mediated Amyloid-beta toxicity Is Associated with an Intermolecular Histidine Bridge. Journal of Biological Chemistry. 281:15145-15154. 2006
  - Dimerisation of N-acetyl-L-tyrosine ethyl ester and Abeta peptides via formation of dityrosine. Free Radical Research. 40(1):1-9. 2006
  - Effect of Linker Length on Avidin Binding to Biotinylated Gramicidin A. International Journal of Peptide Research and Therapeutics. 12(3):243-252. 2006
  - Interfacial properties of the M1 segment of the nicotinic acetylcholine receptor. Biophysical Chemistry. 121:171-176. 2006
  - Membrane interactions of antimicrobial peptides from Australian tree frogs. Biochimica et Biophysica Acta-Biomembranes. 1758:1178-1183. 2006
  - Orientational Order of Australian Spider Silks as Determined by Solid-State NMR. Biopolymers. 82(2):134-143. 2006
  - Structure and Activity of the N-Terminal Region of the Eukaryotic Cytolysin Equinatoxin II. Biochemistry. 45:1818-1828. 2006
2005
- Book Chapters Other
  - Developments in hyphenated spectroscopic methods in natural product profiling. Frontiers in Drug Design and Discovery. Bentham Science Publishers. 113-166. 2005
- Journal Articles Refereed
  - 29Si NMR Study of Structural ordering in Aluminosilicate Geopolymer Gels. Langmuir. 21:3028-3036. 2005
  - Direct Visualization of Membane Leakage Induced by the Antibiotic Peptides: Maculatin, Citropin, and Aurein. Biophysical Journal. 89:1874-1881. 2005
  - Effect of alkali cations on aluminum incorporation in geopolymeric gels. Industrial & Engineering Chemistry Research. 44:832-839. 2005
  - Interaction of the Eukaryotic Pore-forming Cytolysin Equinatoxin II with model membranes: 19F NMR Studies. Journal of Molecular Biology. 347:27-39. 2005
  - Matrix method for analysis of selective NMR pulses. Concepts in Magnetic Resonance - Part A. 25A:1-17. 2005
  - Methionine regulates copper/hydrogen peroxide oxidation products of Aβ. Journal of Peptide Science. 11:353-360. 2005
  - Modeling Speciation in Highly Concentrated Alkaline Silicate Solutions. Industrial & Engineering Chemistry Research. 44:8899-8908. 2005
  - Postsynthesis vapor-phase functionalization of MCM-48 with hexamethyldisilazane and 3-aminopropyldimethylethoxylsilane for bioseparation applications. Journal of Physical Chemistry B. 109:16263-16271. 2005
  - Surface behavior and lipid interaction of Alzheimer β-Amyloid peptide 1-42: A membrane-disrupting peptide. Biophysical Journal. 88:2706-2713. 2005
  - The conformational flexibility of the antibiotic virginiamycin M1. European Biophysics Journal with Biophysics Letters. 34:383-388. 2005
  - The role of Aβ peptides in Alzheimer's disease. Protein and Peptide Letters. 12:513-519. 2005
2004
- Research Book Chapters
  - An introduction to biological solid state NMR. Supramolecular structure and function 8. Kluwer Academic/Plenum Publishers. 145-156. 2004
- Journal Articles Refereed
  - A multidimensional ¹ H NMR investigation of the conformation of methionine-enkephalin in fast-tumbling bicelles. Biophysical Journal. 86:1587-1600. 2004
  - Copper catalysed oxidation of amino acids and Alzheimer's disease. Letters in Peptide Science. 10:405-412. 2004
  - Difference in conformation of virginiamycin M₁ in chloroform and bound form in the 50S ribosome or streptogramin acetyltransferase. Australian Journal of Chemistry. 57:415-418. 2004
  - Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance. Peptides. 25:1035-1054. 2004
  - Metal catalyzed oxidation of tyrosine residues by different oxidation systems of copper/hydrogen peroxide. Journal of Inorganic Biochemistry. 98:173-184. 2004
  - NMR structural elucidation of amino resins. Journal of Applied Polymer Science. 91:3504-3512. 2004
  - Solid-state NMR study of antimicrobial peptides from Australian frogs in phospholipid membranes. European Biophysics Journal with Biophysics Letters. 33:109-116. 2004
  - Solvent affects the conformation of virginiamycin M₁ (pristinamycin IIA, streptogramin A). Organic & Biomolecular Chemistry. 2:2919-2924. 2004
  - Surface behaviour and peptide-lipid interactions of the antibiotic peptides, Maculatin and Citropin. Biochimica et Biophysica Acta-Biomembranes. 1664:31-37. 2004
  - The αM1 segment of the nicotinic acetylcholine receptor exhibits conformational flexibility in a membrane environment. Biochimica et Biophysica Acta-Biomembranes. 1665:40-47. 2004
  - The αM1 transmembrane segment of the nicotinic acetylcholine receptor interacts strongly with model membranes. Magnetic Resonance in Chemistry. 42:148-154. 2004
- Journal Articles Unrefereed
  - Magnetic moments: membrane protein structures by NMR. Chemistry in Australia. 71:4-7. 2004
- Other Refereed Contribution to Refereed Journals
  - Metal-catalyzed oxidative damage and oligomerization of the amyloid-β peptide of Alzheimer's Disease. Australian Journal of Chemistry. 57:511-518. 2004
2003
- Journal Articles Refereed
  - Effects of the eukaryotic pore-forming cytolysin equinatoxin II on lipid membranes and the role of sphingomyelin. Biophysical Journal. 84:2382-2392. 2003
  - Interaction of antimicrobial peptides from Australian amphibians with lipid membranes. Chemistry and Physics of Lipids. 122:107-120. 2003
  - Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions. Biochemistry. 42:5341-5348. 2003
  - Magnetic resonance studies of β-Amyloid peptides. Australian Journal of Chemistry. 56:349-356. 2003
  - Neurotoxic, redox-competent Alzheimer's β-amyloid is released from lipid membrane by methionine oxidation. Journal of Biological Chemistry. 278:42959-42965. 2003
  - Solid-state NMR structural determination of components in an ion channel switch biosensor. Australian Journal of Chemistry. 56:163-166. 2003
  - The aromaticity of ferrocene and some derivatives, ruthenocene and dibenzenechromium as determined via ring current assessment and ¹³ C anisotropic contributions to the ¹ H NMR shielding. New Journal of Chemistry. 27:381-386. 2003
- Other Refereed Contribution to Refereed Journals
  - Solid-state NMR structure determination. IUBMB Life. 55:515-523. 2003
- Conference Papers Refereed
  - Surface coating of MCM-48 via a gas phase reaction with hexamethyldisilazane (HMDS). 493-496. 2003
2002
- Journal Articles Refereed
  - A solid-state NMR study of protein mobility in lyophilized protein-sugar powders. Journal of Pharmaceutical Sciences. 91:943-951. 2002
  - Biophysical studies of a transmembrane peptide derived from the T cell antigen receptor. Letters in Peptide Science. 8:227-233. 2002
  - Solid-state NMR conformational studies of a melittin-inhibitor complex. European Biophysics Journal with Biophysics Letters. 31:383-388. 2002
  - Solid-state NMR relaxation studies of Australian spider silks. Biopolymers. 61:287-297. 2002
- Journal Articles Unrefereed Letters or Notes
  - Solid-state NMR spectroscopy: Principles and applications. Chemistry in Australia. 69:27-28. 2002
2001
- Journal Articles Refereed
  - A metallosupramolecular capsule with the topology of the Tetrahedron, 3³ , assembled from four guanidine-based ligands and twelve cadmium centers. Angewandte Chemie - International Edition. 40:4385-4386. 2001
  - A reexamination of the structure of "Honeycomb Cadmium Cyanide". Journal of Solid State Chemistry. 156:51-56. 2001
  - Solid-state NMR structure determination of melittin in a lipid environment. Biophysical Journal. 81:2752-2761. 2001
  - Solid-state NMR study of aging of Colorbond polymer coating. Polymer. 42:925-930. 2001
  - Synthesis of deuterated aminocaproyl linkers. Australian Journal of Chemistry. 54:747-750. 2001

Research

Investigator on

Contract
- MOU between the University of Melbourne and the University of Brawijaya administered by Chemistry 2013 -
- NOVEL PROTIC IONIC LIQUIDS awarded by CSIRO 2012 - 2015
- Protein-Lipid Cubic Phase Nanoparticals awarded by CSIRO 2012 - 2015
- Structure of membrane proteins awarded by CSIRO 2012 - 2015
- Synthesis of insulin-like peptides awarded by CSIRO 2012 - 2015
- CSIRO PROVIDING SERVICES AT UOM awarded by CSIRO 2011 - 2013
- THE MECHANISM OF MEMBRANE DISRUPTION BY ANTIMICROBIAL PEPTIDES (Discovery Projects) awarded by MONASH UNIVERSITY 2011 - 2013
- RELATING TO CRYSTAL X-RAY STRUCTURE DETERMINATIONS OF BIOLOGICAL SAMPLES CONTAINING PRANA'S CLINICAL CANDIDATE COMPOUNDS awarded by PRANA BIOTECHNOLOGY LTD 2011 -
- MELBOURNE BIOMOLECULAR NMR NETWORK (Linkage Infrastructure (Equipment and Facilities)) awarded by MONASH UNIVERSITY 2009
- ENHANCED NMR RESEARCH, CHARACTERISATION AND ANALYSIS FACILITY (Linkage Infrastructure (Equipment and Facilities)) awarded by MONASH UNIVERSITY 2008 - 2009
- A NATIONAL BIOMEDICAL ELECTRON PARAMAGNETIC RESONANCE AND MOLECULAR IMAGING CENTRE (Linkage Infrastructure (Equipment and Facilities)) awarded by MONASH UNIVERSITY 2007
- DEVELOPMENT OF REACTIVE IONIC LIQUIDS FOR FUTURE INDUSTRIAL APPLICATIONS IN AUSTRALIA (Linkage Projects) awarded by MONASH UNIVERSITY 2006 - 2009
- STRUCTURE AND ACTIVITY OF HOST-DEFENCE PEPTIDES FROM AUSTRALIAN ANURANS: ANTICANCER AGENTS, NEUROPETIDES AND NNOS INHIBITORS (Discovery Projects) awarded by UNIVERSITY OF ADELAIDE 2006 - 2008
- ACQUISITION OF SOLID-STATE NMR SPECTRA ON BEHALF OF ICEUTICA PTY LTD BY PROF. FRANCES SEPAROVIC awarded by ICEUTICA PTY LTD
- ULTRA-HIGH RESOLUTION NMR IMAGING SYSTEM FOR NANOTECHNOLOGY INCLUDING NANOBIOTECHNOLOGY (Linkage Infrastructure (Equipment and Facilities)) awarded by UNIVERSITY OF WESTERN SYDNEY
Grant
- SELECTIVE TARGETING OF MICROBES BY PEPTIDES OF THE INNATE IMMUNE SYSTEM (Project Grants) awarded by UNIVERSITY OF QUEENSLAND 2013 - 2015
- A 700 MHZ NMR SPECTROMETER FOR THE MELBOURNE BIOMOLECULAR NMR NETWORK: A HIGH THROUGHPUT RESOURCE (Linkage Infrastructure (Equipment and Facilities)) awarded by AUST RESEARCH COUNCIL 2012
- ADVANCED BIOPHYSICAL CHARACTERISATION CENTRE (ABCC) (Linkage Infrastructure (Equipment and Facilities)) awarded by RMIT 2012
- ADVANCED CHARACTERISATION OF MATERIALS BY NUCLEAR MAGNETIC RESONANCE (Linkage Infrastructure (Equipment and Facilities)) awarded by AUST RESEARCH COUNCIL 2011 - 2012
- Membrane-associated structure and the effect of metals on Abeta peptide from Alzheimer's disease (Discovery Projects) awarded by AUST RESEARCH COUNCIL 2009 - 2012
- Investigation of the cytotoxic structural determinants of Abeta peptide in Alzheimers Disease (Janssen Cilag Research Grant) awarded by ALZHEIMER'S AUST RESEARCH LTD 2007 - 2008
- MEMBRANE INTERACTIONS AND NEUROTOXICITY OF AMYLOID ABETA PEPTIDES FROM ALZHEIMER S DISEASE. (Discovery Projects) awarded by AUST RESEARCH COUNCIL 2006 - 2008
- Membrane protein structure and interaction facility (Linkage Infrastructure (Equipment and Facilities)) awarded by AUST RESEARCH COUNCIL 2006 - 2008
- Small molecule NMR facility for accelerated drug discovery (Linkage Infrastructure (Equipment and Facilities)) awarded by AUST RESEARCH COUNCIL 2004
- Membrane structure & lipid interactions of the pore-forming toxin Equinatoxin II by NMR (Discovery Projects) awarded by AUST RESEARCH COUNCIL 2003 - 2005
- Amphibian peptides as new antibiotics: structural determinants of antimicrobial activity (Melbourne Research Grants Scheme) administered by Chemistry
- MEMBRANE RECOGNITION OF ANTIMICROBIAL PEPTIDES (Interdisciplinary Seed Grants) awarded by UNIVERSITY OF MELBOURNE
- The location of antimicrobial peptides in phospholipid membranes determined by neutron techniques (Access to Major Facilities Program) awarded by ANSTO

Awards

Education and training

PhD, University of New South Wales 1993
BA(Hons), Macquarie University 1986
BA, Macquarie University 1984

Awards and honors

Fellow of the Biophysical Society, 2012
Fellow of the Australian Academy of Science, 2012
2011 ANZMAG Medal, Australian & New Zealand Society for Magnetic Resonance, 2011
2009 Robertson Award, Australian Society for Biophysics, 2009
Member of the Royal Australian Chemical Institute, 1996

Linkages

International Linkage

Yokohama National University (Exchange)
University of Southampton (Exchange)
University of Michigan (Exchange)
Jawaharlal Nehru University (Exchange; Research)
King's College London (Exchange; Research)
Centre for Cellular and Molecular Biology (Exchange; Research)
University of Alberta (Exchange; Research)
University of Arkansas at Fayetteville (Exchange; Research)
Birkbeck College (Exchange; Research)
University of Durham (Exchange; Research)
University of Oxford (Exchange; Research)
University of California - San Diego (Exchange; Research)
University of Chicago (Exchange; Research)
University of Minnesota (Exchange; Research)
San Diego State University (Exchange; Research; Teaching)
Research Institute of Ophthalmology (Exchange; Research; Techinical Assistance/Training)
Laval University (Exchange; Research; Techinical Assistance/Training)
Karlsruhe Institute of Technology (Exchange; Research; Techinical Assistance/Training)
Utrecht University (Exchange; Teaching; Techinical Assistance/Training)
University of Split (Exchange; Techinical Assistance/Training)
National University of Cordoba (Research)
University of Ljubljana (Research)

Supervision

Available for supervision

Y

Contact Details
- fs@unimelb.edu.au
- 83447137
- fax: 93475180
- Location
  - Level: 02 Room: 258, Chemistry - Old, Parkville
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