Has subject area
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For 2008 6 Digit Code
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Seo 2008 6 Digit Code
PROF GLENN BROWNING
Positions
- Academic, Veterinary Science Faculty
- Veterinary Virology (Rotavirus, Herpesvirus, Circovirus, Coronavirus, Calicivirus)
- Veterinary Bacteriology (Rhodococcus, Escherichia coli, Salmonella, Mycoplasma,)
- Treatment, prevention, diagnosis and control of bacterial and viral diseases of animals
- Molecular pathogenesis of infectious disease
- Mycoplasmas of humans and animals
- Diarrhoea viruses of animals
- Chlamydia in animals
- Animal vaccines
- Bovine mastitis
- Rhodococcus equine infections in horses
Overview
Affiliation
Member of
- Australian Society for Microbiology. Member 2006 -
- American Society for Microbiology. Member 1999 -
- Society for General Microbiology. Member 1996 -
- International Organisation for Mycoplasmology. Member 1994 -
- Australian Veterinary Association. Member 1983 -
Publications
Selected publications
2013
Journal Articles Refereed
2012
Journal Articles Refereed
- A novel transposon construct expressing PhoA with potential for studying protein expression and translocation in Mycoplasma gallisepticum. BMC Microbiology. 12:1-12. 2012
- Air sampling in the breathing zone of neonatal foals for prediction of subclinical Rhodococcus equi infection. Equine Veterinary Journal. 44:203-206. 2012
- Attenuated vaccines can recombine to form virulent field viruses. Science. 337:188-188. 2012
- Comparative analysis of the complete genome sequences of two Australianorigin live attenuated vaccines of infectious laryngotracheitis virus. Vaccine. 29:9583-9587. 2012
- Detection of a second novel gammaherpesvirus in a free-ranging koala (Phascolarctos cinereus ). Journal of Wildlife Diseases. 48:226-229. 2012
- Effect of simulated stages of the canine oestrous cycle on Escherichia coli binding to canine endometrium. Reproduction in Domestic Animals. 47:331-334. 2012
- Histochemical and morphometric characterization of bronchopneumonia in calves caused by infection with Mycoplasma bovis. Veterinary Microbiology. 158:220-224. 2012
- Kinetics of transcription of infectious laryngotracheitis virus genes. Comparative Immunology Microbiology and Infectious Diseases. 35:103-115. 2012
- Molecular epidemiology of Mannheimia haemolytica and Mannheimia glucosida associated with ovine mastitis. Journal of Veterinary Diagnostic Investigation. 24:730-734. 2012
- Safety and vaccine efficacy of a glycoprotein G deficient strain of infectious laryngotracheitis virus delivered in ovo. Vaccine. 30:7193-7198. 2012
- TonB is essential for virulence in avian pathogenic Escherichia coli. Comparative Immunology Microbiology and Infectious Diseases. 35:129-138. 2012
- Uropathogenic virulence factor FimH facilitates binding of uteropathogenic Escherichia coli to canine endometrium. Comparative Immunology Microbiology and Infectious Diseases. 35:461-467. 2012
- Viral enteritis in domestic animals. Microbiology Australia. 33:53-55. 2012
2011
Journal Articles Refereed
- Comparative in vivo safety and efficacy of a glycoprotein G-deficient candidate vaccine strain of infectious laryngotracheitis virus delivered via eye drop. Avian Pathology. 40:411-417. 2011
- Detection of a novel gammaherpesvirus in koalas (Phascolarctos cinereus ). Journal of Wildlife Diseases. 47:787-791. 2011
- Development and immunogenicity of recombinant GapA+ Mycoplasma gallisepticum vaccine strain ts-11 expressing infectious bronchitis virus-S1 glycoprotein and chicken interleukin-6. Vaccine. 29:3197-3205. 2011
- Development of a SYBR Green quantitative polymerase chain reaction assay for rapid detection and quantification of infectious laryngotracheitis virus. Avian Pathology. 40:237-242. 2011
- First complete genome sequence of infectious laryngotracheitis virus. BMC Genomics. 12:1-6. 2011
- GapA+ Mycoplasma gallisepticum ts-11 has improved vaccine characteristics. Microbiology-SGM. 157:1740-1749. 2011
- Horizontal transmission dynamics of a glycoprotein G deficient candidate vaccine strain of infectious laryngotracheitis virus and the effect of vaccination on transmission of virulent virus. Vaccine. 29:5699-5704. 2011
- Infectious bronchitis viruses with naturally occurring genomic rearrangement and gene deletion. Archives of Virology. 156:245-252. 2011
- Outbreak of equine endometritis caused by a genotypically identical strain of Pseudomonas aeruginosa. Journal of Veterinary Diagnostic Investigation. 23:1236-1239. 2011
- Preface: Pathogenesis of bacterial diseases of animals. Veterinary Microbiology. 153:1-1. 2011
- The central role of lipoproteins in the pathogenesis of mycoplasmoses. Veterinary Microbiology. 153:44-50. 2011
- The role of Mannheimia species in ovine mastitis. Veterinary Microbiology. 153:67-72. 2011
2010
Research Book Chapters
- Mycoplasma. Pathogenesis of Bacterial Infection in Animals. Wiley-Blackwell Publishing. 549-573. 2010
Journal Articles Refereed
- Mannheimia species associated with ovine mastitis. Journal of Clinical Microbiology. 48:3419-3422. 2010
- Application of high-resolution melt curve analysis for classification of infectious bronchitis viruses in field specimens. Australian Veterinary Journal. 88:408-413. 2010
- Evaluation of immunological responses to a glycoprotein G deficient candidate vaccine strain of infectious laryngotracheitis virus. Vaccine. 28:1325-1332. 2010
- Naturally occurring recombination between distant strains of infectious bronchitis virus. Archives of Virology. 155:1581-1586. 2010
2009
Journal Articles Refereed
- Detection of virulent Rhodococcus equi in exhaled air samples from naturally infected foals. Journal of Clinical Microbiology. 47:734-737. 2009
- Genetic characterization of Cryptosporidium parvum from calves by mutation scanning and targeted sequencing - zoonotic implications. Electrophoresis. 30:2640-2647. 2009
- Plasmid-borne virulence-associated genes have a conserved organization in virulent strains of avian pathogenic Escherichia coli. Journal of Clinical Microbiology. 47:2513-2519. 2009
- The conserved portion of the putative virulence region contributes to virulence of avian pathogenic Escherichia coli. Microbiology. 155:450-460. 2009
Patents
2008
Journal Articles Refereed
- Comparison of the safety and protective efficacy of vaccination with glycoprotein-G-deficient infectious laryngotracheitis virus delivered via eye-drop, drinking water or aerosol. Avian Pathology. 37:83-88. 2008
- Development and immunogenicity of recombinant Mycoplasma gallisepticum vaccine strain ts-11 expressing chicken IFN-y. Vaccine. 26:5449-5454. 2008
- Development of a replicable ori C plasmid for Mycoplasma gallisepticum and Mycoplasma imitans , and gene disruption through homologous recombination in M. gallisepticum. Microbiology. 154:2571-2580. 2008
- Differential expression of lipoprotein genes in Mycoplasma pneumoniae after contact with human lung epithelial cells, and under oxidative and acidic stress. BMC Microbiology. 8. 2008
- Evaluation of chicken anaemia virus mutants as potential vaccine strains in 1-day-old chickens. Avian Pathology. 37:109-114. 2008
- Infectious bronchitis viruses with a novel genomic organization. Journal of Virology. 82:2013-2024. 2008
2007
Journal Articles Refereed
- Mycoplasma hyopneumoniae mhp379 is a Ca2+ - dependent, sugar-nonspecific exonuclease exposed on the cell surface. Journal of Bacteriology. 189:3414-3424. 2007
- Attenuation of chicken anemia virus by site-directed mutagenesis of VP2. Journal of General Virology. 88:2168-2175. 2007
- Comparison of two selective media for the recovery, isolation, enumeration and differentiation of Rhodococcus equi. Veterinary Microbiology. 119:324-329. 2007
- Glycoprotein G deficient infectious laryngotracheitis virus is a candidate attenuated vaccine. Vaccine. 25:3561-3566. 2007
- IFN-y enhances immune responses to E coli infection in the chicken. Journal of Interferon and Cytokine Research. 27:937-946. 2007
Patents
2006
Journal Articles Refereed
- A glycoprotein I- and glycoprotein E-deficient mutant of infectious laryngotracheitis virus exhibits impaired cell-to-cell spread in cultured cells. Archives of Virology. 151:1281-1289. 2006
- A model for cystic endometrial hyperplasia/pyometra complex in the bitch. Theriogenology. 66:1530-1536. 2006
- Age related differences in the immune response to vaccination and infection with Mycoplasma gallisepticum. Vaccine. 24:1687-1692. 2006
- Associations between the ecology of virulent Rhodococcus equi and the epidemiology of R. equi pneumonia on Australian Thoroughbred farms. Applied and Environmental Microbiology. 72:6152-6160. 2006
- Clinical evaluation of a peptide-ELISA based upon N-terminal B-cell epitope of the VapA protein for diagnosis of Rhodococcus equi pneumonia in foals. Journal of Veterinary Medicine Series B - Infectious Diseases and Veterinary Public Health. 53:126-132. 2006
- Comparison of concentrations of Rhodococcus equi and virulent R. equi in air of stables and paddocks on horse breeding farms in a temperate climate. Equine Veterinary Journal. 38:263-265. 2006
- Glycoprotein G is a virulence factor in infectious laryngotracheitis virus. Journal of General Virology. 87:2839-2847. 2006
- IL-18 expression in pigs following infection with Mycoplasma hyopneumoniae. Journal of Interferon and Cytokine Research. 26:637-644. 2006
- Lipoprotein multigene families in Mycoplasma pneumoniae. Journal of Bacteriology. 188:5393-5399. 2006
- Organization of the Mycoplasma synoviae WVU 1853T vlhA gene locus. Avian Pathology. 35:53-57. 2006
- Rapid differentiation of current infectious bronchitis virus vaccine strains and field isolates in Australia. Australian Veterinary Journal. 84:59-62. 2006
- Site-directed mutagenesis of the VP2 gene of Chicken anemia virus affects virus replication, cytopathology and host-cell MHC class 1 expression. Journal of General Virology. 87:823-831. 2006
- The cellular immune response in the tracheal mucosa to Mycoplasma gallisepticum in vaccinated and unvaccinated chickens in the acute and chronic stages of disease. Vaccine. 24:2627-2633. 2006
- Typing infectious bronchitis virus strains using reverse transcription-polymerase chain reaction and restriction fragment length polymorphism analysis to compare the 3' 7.5 kb of their genomes. Avian Pathology. 35:63-69. 2006
- Viral load in 1-day-old and 6-week-old chickens infected with chicken anaemia virus by the intraocular route. Avian Pathology. 35:471-474. 2006
Patents
2005
Research Book Chapters
- Phenotypic Diversity and Cell Invasion in Host Subversion by Pathogenic Mycoplasmas. Mycoplasmas Molecular Biology Pathogenicity and Strategies for Control. Horizon Bioscience. 45-45. 2005
- Vaccines to Control Mycoplasmosis. Mycoplasmas Molecular Biology Pathogenicity and Strategies for Control. Horizon Bioscience. 29-29. 2005
Journal Articles Refereed
- Mutation of chicken anemia virus VP2 differentially affects serine/threonine and tyrosine protein phosphatase activities. Journal of General Virology. 86:623-630. 2005
- The vlhA loci of Mycoplasma synoviae are confined to a restricted region of the genome. Microbiology. 151:935-940. 2005
2004
Book Chapters Other
- Mycoplasma. Pathogenesis of bacterial infections in animals. Blackwell Publishing Asia. 397-414. 2004
Journal Articles Refereed
- Mycoplasma hyopneumoniae p65 surface lipoprotein is a lipolytic enzyme with a preference for shorter-chain fatty acids. Journal of Bacteriology. 186:5790-5798. 2004
- Association of iss and iucA , but not tsh , with plasmid-mediated virulence of avian pathogenic Escherichia coli. Infection and Immunity. 72:6554-6560. 2004
- Identification and differentiation of avirulent and virulent Rhodococcus equi using selective media and colony blotting DNA hybridization to determine their concentrations in the environment. Veterinary Microbiology. 100:121-127. 2004
Journal Articles Unrefereed
- Is Chlamydophila felis a significant zoonotic pathogen?. Australian Veterinary Journal. 82:695-696. 2004
Conference Papers Unrefereed
- Using biotechnology to control animal diseases. Proceedings of The 11th Int Conf of The Association of Institutions for Tropical Veterinary Medicine. 31-32. 2004
2003
Journal Articles Refereed
- Embryonic age influences the capacity for cytokine induction in chicken thymocytes. Immunology. 110:358-367. 2003
- Homologue of macrophage-activating lipoprotein in Mycoplasma gallisepticum is not essential for growth and pathogenicity in tracheal organ cultures. Journal of Bacteriology. 185:2538-2547. 2003
- It takes more than metadata and stories of success: Understanding barriers to reuse of computer facilitated learning resources. Australian Journal of Educational Technology. 19:72-86. 2003
- Multiplex polymerase chain reaction as a mastitis screening test for Staphylococcus aureus, Streptococcus agalactiae, Streptococcus dysgalactiae and Streptococcus uberis in bulk milk samples. Journal of Dairy Research. 70:149-155. 2003
- The complete genome sequence of the avian pathogen Mycoplasma gallisepticum strain >R low. Microbiology. 149:2307-2316. 2003
- Uropathogenic virulence factors in isolates of Escherichia coil from clinical cases of canine pyometra and feces of healthy bitches. Veterinary Microbiology. 94:57-69. 2003
- Variation between Pathogenic Serovars within Salmonella Pathogenicity Islands. Journal of Bacteriology. 185:3624-3635. 2003
2002
Book Chapters Other
- Genetic Mechanisms of Surface Variation. Molecular Biology and Pathogenicity of Mycoplasmas. Kluwer Academic/Plenum Publishers. 417-443. 2002
Journal Articles Refereed
- Chicken Anemia Virus VP2 Is a Novel Dual Specificity Protein Phosphatase*. Journal of Biological Chemistry. 277:39566-39573. 2002
- Detection of Antibodies to Mycoplasma gallisepticum Vaccine ts-11 by an Autologous pMGA Enzyme-Linked Immunosorbent Assay. Avian Diseases. 46:405-411. 2002
- Improved detection of antibodies to Mycoplasma synoviae vaccine MS-H using an autologous recombinant MSPB enzyme-linked immunosorbent assay. Avian Pathology. 31:611-617. 2002
- Induction of enzootic pneumonia in pigs by the administration of an aerosol of in vitro-cultured Mycoplasma hyopneumoniae. Veterinary Record. 150:9-11. 2002
2001
Journal Articles Refereed
- Detection of feline calicivirus, feline herpesvirus 1 and Chlamydia psittaci mucosal swabs by multiplex RT-PCR/PCR. Veterinary Microbiology. 81:95-108. 2001
- Epidemiology of Rhodococcus equi Strains on Thoroughbred Horse Farms. Applied and Environmental Microbiology. May:2167-2175. 2001
- Genotyping Cryptosporidium parvum by single-strand conformation polymorphism analysis of ribosomal and heat shock gene regions. Electrophoresis. 22:433-437. 2001
- Molecular Epidemiology of Streptococcus uberis Isolates from Dairy Cows with Mastitis. Journal of Clinical Microbiology. 39:1460-1466. 2001
- Molecular epidemiology of Salmonella Heidelberg in an equine hospital. Veterinary Microbiology. 80:85-98. 2001
- Multiplex Polymerase Chain Reaction Assay for Simultaneous Detection of Staphylococcus aureus and Streptococcal Causes of Bovine Mastitis. Journal of Dairy Science. 84:1140-1148. 2001
- Rapid PCR detection of Salmonella in horse faecal samples. Veterinary Microbiology. 79:63-74. 2001
Research
Investigator on
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Consultancy
- PFIZER - TESTING SERVICES awarded by UOM COMMERCIAL LTD
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Contract
- Testing a novel adjuvant to improve immune responses to Salmonella vaccination awarded by POULTRY CRC LTD 2012 - 2013
- DEVELOPMENT OF AN ATTENUATED VACCINE TO CONTROL THE EMERGING BOVINE RESPIRATORY PATHOGEN MYCOPLASMA BOVIS awarded by FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH 2011 -
- AVIAN ESCHERICHIA COLI ISOLATES awarded by IOWA STATE UNIVERSITY 2010 -
- LICENCE TO A FAMILY OF PATENTS AROUND 2001-2002 CHICKEN ANEMIA VIRUS VACCINE awarded by PFIZER AUST PTY LTD 2010 -
- PARTICIPANTS AGREEMENT - POULTRY CRC MARK 2 awarded by POULTRY CRC LTD 2010 -
- ISOLATION OF A BOVINE ROTAVIRUS STRAIN SUITABLE FOR VACCINE DEVELOPMENT awarded by INTERVET AUSTRALIA PTY LTD 2007 - 2008
- AMD - POSTGRADUATE SCHOLARSHIP - KELLY ANNE TIVENDALE - GENOMIC APPROACHES TO CONTROL COLIBACILLOSIS (MR1095) awarded by POULTRY CRC LTD 2007
- POSTGRADUATE SCHOLARSHIP AGREEMENT FOR CHI-WEN TSENG - DEVELOPMENT OF NEW MYCOPLASMA BASED VACCINES awarded by POULTRY CRC LTD 2006 - 2007
- AP CRC PROJECT 03-12 :TOWARDS RAPID REGISTRATION OF A LIVE ATTENUATED PASTEURELLA MULTICODA VACCINE awarded by BIOPROPERTIES AUST PTY LTD 2004 - 2007
- Australian Poultry CRC 03-08: Assessment of Chicken anaemia Virus mutants as Vaccine Strains awarded by POULTRY CRC LTD 2004 - 2007
- STUDENTSHIP-ADAM KARPALA: RNA INTERFERENCE TO CONTROL VIRAL DISEASES IN CHICKENS awarded by POULTRY CRC LTD 2004 - 2007
- AP CRC PROJECT 03-09 :GENOMIC APPROACHES TO DEVELOPMENT OF NOVEL VACCINES awarded by POULTRY CRC LTD 2003 - 2006
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Grant
- AUSTRALIAN POULTRY BIOLOGICALS COMMERCIALISATION CENTRE (APBCC) (R & D Proposal) awarded by POULTRY CRC LTD 2011 - 2015
- Development and validation of a qRT-PCR assay for the detection of feline calicivirus (FCV) in clinical samples. (Research Grants) awarded by FELINE HEALTH RESEARCH FUND 2011 - 2012
- Avoiding the Immune Response - Lessons from "Simple" Bacteria (Discovery Projects) awarded by AUST RESEARCH COUNCIL 2010 - 2014
- TOWARDS COMMERCIALISATION OF A NEXT-GENERATION ILTV VACCINE AND DIFFERENTIAL ELISA (R & D Proposal) awarded by POULTRY CRC LTD 2010 - 2013
- Structural and functional investigations into a novel chemokine binding protein encoded by evolutionarily diverse alphaherpesviruses (Discovery Projects) awarded by AUST RESEARCH COUNCIL 2009 - 2013
- Development of an attenuated vaccine to control the emerging bovine respiratory pathogen Mycoplasma bovis (Linkage Projects) awarded by AUST RESEARCH COUNCIL 2009 - 2012
- Improving control of infectious laryngotracheitis virus in Australian broiler flocks. (Research Priorities Program) awarded by RURAL INDUSTRIES R & D CORPORATION 2009 - 2012
- DEVELOPING NOVEL ANTIGEN DELIVERY SYSTEMS; ILTV AS A VACCINE VECTOR (R & D Proposal) awarded by POULTRY CRC LTD 2009
- Investigations into a novel recombinant vaccine to control infectious laryngotracheitis (R & D Proposal) awarded by POULTRY CRC LTD 2009
- Using transgenic plant-based production and delivery systems to develop an avian influenza vaccine (Linkage Projects) awarded by AUST RESEARCH COUNCIL 2006 - 2009
- Blocking immune responses: a critical factor in herpesvirus virulence? (Discovery Projects) awarded by AUST RESEARCH COUNCIL 2006 - 2008
- DETECTING THE PRESENCE OF STREPTOCOCCUS AGALACTIAE IN BULK VAT MILK USING ROUTINELY COLLECTED MILK SAMPLES - Populated from Themis conversion (Project Grants) awarded by DAIRY AUSTRALIA 2004 - 2008
- Development and assessment of chimaeric feline caliciviruses as vaccines (Linkage Projects) awarded by AUST RESEARCH COUNCIL 2004 - 2008
- Equine infectious respiratory disease after long distance confined transportation (Linkage Projects) awarded by AUST RESEARCH COUNCIL 2004 - 2008
- Development of an attenuated infectious laryngotracheitis virus vaccine (Linkage Projects) awarded by AUST RESEARCH COUNCIL 2003 - 2006
- Management strategies for reducing risk of rhodococcal pneumonia on studs (Research Priorities Program) awarded by RURAL INDUSTRIES R & D CORPORATION 2003 - 2006
- Avian leukosis subgroup-J (ALV-J): Epidemiological studies for eradication of ALV-J from Australian broiler breeder flocks 2003-5 (Research Priorities Program) awarded by RURAL INDUSTRIES R & D CORPORATION 2003 - 2005
- FUNCTIONAL TARGETS FOR INHIBITORY ANTIBODIES ON THE CELL SURFACE OF MYCOPLASMA PNEUMONIAE (Melbourne Research Grants Support Scheme) awarded by UNIVERSITY OF MELBOURNE
Awards
Education and training
- PhD, University of Melbourne 1988
- DipVetClinStud, University of Sydney 1984
- BVSc (Hons I), University of Sydney 1983
Awards and honors
- Member of the Australian Society for Microbiology, 2005
- Humboldt Research Fellowship, Alexander von Humboldt Foundation, 1998
- Meritorious Service Award, Australian Veterinary Association, 1997
Linkages
International Linkage
- Ruprecht-Karls-Universitaet Heidelberg (Exchange; Research)
- Universite Toulouse (Research)
Supervision
Available for supervision
- Y
- Contact Details
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glenfb@unimelb.edu.au
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0383447342
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fax: 0383447374
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After hours: Media Only (login required)
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Location
- Level: 03 Room: 301, Vet Preclinical Centre, Parkville
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